Yadav, Chanchal Yack, Jayne E. Smith, Myron L.
Published in
BMC Research Notes
Objective Group-living plays a key role in the success of many insects, but the mechanisms underlying group formation and maintenance are poorly understood. Here we use the masked birch caterpillar, Drepana arcuata, to explore genetic influences on social grouping. These larvae predictably transition from living in social groups to living solitaril...
Guo, Qianqian Zheng, Junjun Ba, Hengxing Sun, Hongmei Zhai, Jingjie Wang, Wenying Li, Chunyi
Published in
Frontiers in Cell and Developmental Biology
Deer antlers are male secondary sexual characters that develop to become bone; they are unique appendages that, once lost, can fully regenerate from the permanent bony protuberances or pedicles. Pedicle periosteum (PP) is the tissue that gives rise to the regenerating antlers with three differentiation stages, namely, dormant (DoPP), potentiated (P...
Feng, ShangLe Li, XueNan Wang, He Li, WenJuan Bai, ZhiYi
Published in
Frontiers in Marine Science
Cyclin dependent kinase 6 (CDK6) is a serine/threonine kinase that plays important roles in cell cycle progression and differentiation. In this study, full-length cDNA of Hc-CDK6 was obtained from freshwater pearl mussels (Hyriopsis cumingii, Hc) with 3´,5´ rapid-amplification of cDNA ends (RACE). The Hc-CDK6 expression profiles were analyzed with ...
Li, Yan Wang, Sha-Sha Wang, Su Wang, Shi-Gui Tang, Bin Liu, Fang
Published in
Insect science
Glucose is vital to embryogenesis, as are glucose transporters. Glucose transporter 4 (Glut4) is one of the glucose transporters, which is involved in rapid uptake of glucose by various cells and promotes glucose homeostasis. Although energy metabolism in insect reproduction is well known, the molecular mechanism of Glut4 in insect reproduction is ...
Martinson, Ellen O Werren, John H Egan, Scott P
Published in
Molecular ecology
Every organism on Earth depends on interactions with other organisms to survive. In each of these interactions, an organism must utilize the limited toolbox of genes and proteins it possesses to successfully manipulate or cooperate with another species, but it can also co-opt the genome machinery of its partner to expand its available tools. Insect...
Al-Farsi, Halema Al-Azwani, Iman Malek, Joel A. Chouchane, Lotfi Rafii, Arash Halabi, Najeeb M.
Published in
Journal of Translational Medicine
Background Mutated and non-mutated genes interact to drive cancer growth and metastasis. While research has focused on understanding the impact of mutated genes on cancer biology, understanding non-mutated genes that are essential to tumor development could lead to new therapeutic strategies. The recent advent of high-throughput whole genome sequen...
Bacchetta, Justine Wood, Kyle D
Published in
Clinical Kidney Journal
Oxalate crystals in the kidney were first described in 1925. Since then, many major milestones have been reached in the understanding of genetic primary hyperoxaluria(s). Primary hyperoxaluria type 1 (PH1) is an autosomal recessive disease due to a mutation in the AGXT gene, which encodes the hepatic peroxisomal enzyme alanine-glyoxylate aminotrans...
Gupta, Asheeta Somers, Michael J G Baum, Michelle A
Published in
Clinical Kidney Journal
Supportive treatment for primary hyperoxaluria type 1 (PH1) focuses on high fluid intake and crystallization inhibitors. A subset of patients with specific PH1 genotypes (c.508G>A and c.454T>A) will respond to pyridoxine, defined as a >30% reduction in urinary oxalate excretion. Response to pyridoxine is variable and in some patients, urinary oxala...
Halder, Koushik Chaudhuri, Abira Abdin, Malik Z. Majee, Manoj Datta, Asis
Published in
Frontiers in Plant Science
RNA interference (RNAi) has been exploited by scientists worldwide to make a significant contribution in the arena of sustainable agriculture and integrated pest management. These strategies are of an imperative need to guarantee food security for the teeming millions globally. The already established deleterious effects of chemical pesticides on h...
Sánchez-Arcila, Juan C. Jensen, Kirk D. C.
Published in
Frontiers in Cellular and Infection Microbiology
Forward genetic approaches have been widely used in parasitology and have proven their power to reveal the complexities of host-parasite interactions in an unbiased fashion. Many aspects of the parasite’s biology, including the identification of virulence factors, replication determinants, antibiotic resistance genes, and other factors required for...