Zhang, Jinjin Chen, Xiaoqing Chen, Hongbin Li, Rongrong Xu, Pan Lv, Changjun Liu, Bo Song, Xiaodong
Published in
Pharmaceutical Biology
Context Pulmonary fibrosis (PF) is a highly heterogeneous and lethal pathological process having no effective drug. Engeletin exerts multiple biological activities including anti-inflammatory and lung repair. Whether engeletin has therapeutic effects on PF remains unclear. Objective Examining effect and mechanism of engeletin on PF in vivo and in v...
Akbari, Fatemeh Peymani, Maryam Salehzadeh, Ali Ghaedi, Kamran
Published in
Cancer Cell International
BackgroundPathogenesis of colorectal cancer (CRC) is connected to deregulation of apoptosis while the effect of lncRNAs, as critical regulatory molecules, on this pathway is not clear well. The present study aimed to identify differential expression of genes and their related lncRNAs which are significantly associated with intrinsic apoptotic pathw...
Jha, Monica Roy, Swarup Kalita, Jugal K
Published in
Computers in biology and medicine
Many complex diseases occur due to genetic factors. A perturbation in the pathway of gene interactions leads to such disorders. Even though a group of genes is responsible, a few significant genes act as a biomarker for disease, perturbing the healthy network. Identifying such marker genes or a set of genes that play a pivotal role in diseases help...
Xie, Longxiang Wang, Liuyang Zhu, Wan Zhao, Jing Guo, Xiangqian
Published in
Frontiers in Oncology
Mui, Kai-Meng Khaw, Mei-Kum Mohd-Yasin, Faisal
Published in
Micromachines
We present the design of a power management integrated circuit that processes harvested energy from radio frequency waves and piezoelectric vibrations. The rectification of piezoelectric and RF sources has a power conversion efficiency (PCE) of 87.73% and 74.70%, respectively. The asynchronous and microcontroller-less integrated circuit (IC) is des...
Temple, Mark D.
Published in
BMC Bioinformatics
BackgroundThis paper describes a web based tool that uses a combination of sonification and an animated display to inquire into the SARS-CoV-2 genome. The audio data is generated in real time from a variety of RNA motifs that are known to be important in the functioning of RNA. Additionally, metadata relating to RNA translation and transcription ha...
Sa, Kyu Jin Choi, Ik-Young Lee, Ju Kyong
Published in
Genomics & informatics
Maize seed pigmentation is one of the important issue to develop maize seed breeding. The differently gene expression was characterized and compared for three inbred lines, such as the pigment accumulated seed (CM22) and non-pigmented seed (CM5 and CM19) at 10 days after pollination. We obtained a total of 63,870, 82,496, and 54,555 contigs by de n...
Wang, Qi Jia, Feng Zhang, Xia Wang, Xiaohua Li, Jinhe Wang, Jinshui
Published in
Food science & nutrition
The rapid development of transcriptome sequencing technology has contributed to the discovery of numerous genes in plant; however, the role of gene expression in postharvest wheat remains largely unexplored. In this study, differentially expressed genes (DEGs) were identified by RNA-seq in different quality wheats. The 102.6 Gb clean reads had been...
Shen, Zhou Yang, Yiling Yang, Siqi Zhang, Guangxu Xiao, Shaobo Fu, Zhen F. Peng, Guiqing
Published in
Viruses
Non-structural protein 1 (nsp1) is only characterized in alphacoronaviruses (α-CoVs) and betacoronaviruses (β-CoVs). There have been extensive researches on how the β-CoVs nsp1 regulates viral virulence by inhibiting host protein synthesis, but the regulatory mechanism of the α-CoVs nsp1 is still unclear. Here, we report the 2.1-Å full-length cryst...
Biswas, Nidhan K Majumder, Partha P
Published in
The Indian journal of medical research
SARS-CoV-2 (Severe acute respiratory syndrome coronavirus-2) is evolving with the progression of the pandemic. This study was aimed to investigate the diversity and evolution of the coronavirus SARS-CoV-2 with progression of the pandemic over time and to identify similarities and differences of viral diversity and evolution across geographical regi...
