出芽酵母uS7/Rps5のSer223のリン酸化によるリボソームの成熟及び翻訳制御機構
学位規則第4条第1項該当
Unraveling the mechanisms behind the packaging of RNA into exosomes
Exosomes are small extracellular vesicles of endosomal origin of about 100nm of diameter. They are used by the cells to transfer information and can contain a wide range of biomolecules. Among many others, exosomes carry coding and non-coding RNAs. The aim of this study is to unravel the mechanisms behind the exosomal encapsulation of these biomole...
Unraveling the mechanisms behind the packaging of RNA into exosomes
Exosomes are small extracellular vesicles of endosomal origin of about 100nm of diameter. They are used by the cells to transfer information and can contain a wide range of biomolecules. Among many others, exosomes carry coding and non-coding RNAs. The aim of this study is to unravel the mechanisms behind the exosomal encapsulation of these biomole...
Unraveling the mechanisms behind the packaging of RNA into exosomes
Exosomes are small extracellular vesicles of endosomal origin of about 100nm of diameter. They are used by the cells to transfer information and can contain a wide range of biomolecules. Among many others, exosomes carry coding and non-coding RNAs. The aim of this study is to unravel the mechanisms behind the exosomal encapsulation of these biomole...
Defining the earliest step of cardiovascular lineage segregation by single-cell RNA-seq.
...
Mouse heart development arises from Mesp1 expressing cardiovascular progenitors (CPs) that are specified during gastrulation. The molecular processes that control early regional and lineage segregation of CPs remain unclear. Here, we performed single cell RNA-sequencing of WT and Mesp1 null CPs. We showed that Mesp1 CPs are molecularly distinct and...
Extraction and Analysis of RNA Isolated from Pure Bacteria-Derived Outer Membrane Vesicles
Outer membrane vesicles (OMVs) are released by commensal as well as pathogenic Gram-negative bacteria. These vesicles contain numerous bacterial components, such as proteins, peptidoglycans, lipopolysaccharides, DNA, and RNA. To examine if OMV-associated RNA molecules are bacterial degradation products and/or are functionally active, it is necessar...
Extraction and Analysis of RNA Isolated from Pure Bacteria-Derived Outer Membrane Vesicles
Outer membrane vesicles (OMVs) are released by commensal as well as pathogenic Gram-negative bacteria. These vesicles contain numerous bacterial components, such as proteins, peptidoglycans, lipopolysaccharides, DNA, and RNA. To examine if OMV-associated RNA molecules are bacterial degradation products and/or are functionally active, it is necessar...
Extraction and Analysis of RNA Isolated from Pure Bacteria-Derived Outer Membrane Vesicles
Outer membrane vesicles (OMVs) are released by commensal as well as pathogenic Gram-negative bacteria. These vesicles contain numerous bacterial components, such as proteins, peptidoglycans, lipopolysaccharides, DNA, and RNA. To examine if OMV-associated RNA molecules are bacterial degradation products and/or are functionally active, it is necessar...
Homologous VapC Toxins Inhibit Translation and Cell Growth by Sequence-Specific Cleavage of tRNAfMet.
Published in Journal of bacteriology
Type II toxin-antitoxin (TA) systems play a critical role in the establishment and maintenance of bacterial dormancy. They are composed of a protein toxin and its cognate protein antitoxin. They function to regulate growth under conditions of stress, such as starvation or antibiotic treatment. As cellular proteases degrade the antitoxin, which norm...
An Efficient, Large-Scale Survey of Hepatitis C Viremia in the Democratic Republic of the Congo Using Dried Blood Spots....
...Published in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
DBS-based HCV testing represents a useful tool for the diagnosis and surveillance of HCV viremia and can easily be incorporated into specimen referral systems. Among adults ≥40 years of age in the DRC, 100000-200000 may have active infection and be eligible for treatment.
