Published in Sensors (Basel, Switzerland)
Time series forecasting is a very vital research topic. The scale of time series in numerous industries has risen considerably in recent years as a result of the advancement of information technology. However, the existing algorithms pay little attention to generating large-scale time series. This article designs a state causality and adaptive cova...
Published in Polymers
Chitosan is the deacetylated form of chitin regarded as one of the most abundant polymers and due to its properties, both chitosan alone or in combination with bioactive substances for the production of biodegradable films and coatings is gaining attention in terms of applications in the food industry. To enhance the antimicrobial and antioxidant p...
Published in Sensors (Basel, Switzerland)
The cardiopulmonary exercise test (CPET) constitutes a gold standard for the assessment of an individual's cardiovascular fitness. A trend is emerging for the development of new machine-learning techniques applied to the automatic process of CPET data. Some of these focus on the precise task of detecting the exercise thresholds, which represent imp...
Published in Sensors (Basel, Switzerland)
Vehicle detection and tracking technology plays an important role in intelligent transportation management and control systems. This paper proposes a novel vehicle detection and tracking method for small target vehicles to achieve high detection and tracking accuracy based on the attention mechanism. We first develop a new vehicle detection model (...
Organoid cultures could constitute a valuable in vitro model to explore new treatments for canine (c) medullary thyroid carcinoma (MTC). The study's objectives were to estab-lish and characterize 3D organoid cultures of cMTC using histology and immunohisto-chemistry (IHC) and to evaluate the effect of antitumor drugs on organoids' viability. Five c...
status: accepted
Immunotherapies, in particular immune checkpoint blockade (ICB), have improved the clinical outcome of cancer patients, although many fail to mount a durable response. Several resistance mechanisms have been identified, but our understanding of the requirements for a robust ICB response is incomplete. We have engineered an MHC I/antigen: TCR-matche...
Chromone has emerged as one of the most important synthetic scaffolds for antitumor activity, which promotes the development of candidate drugs with better activity. In this study, a series of nitrogen mustard derivatives of chromone were designed and synthesised, in order to discover promising anti-breast tumour candidates. Almost all target deriv...
Chromone has emerged as one of the most important synthetic scaffolds for antitumor activity, which promotes the development of candidate drugs with better activity. In this study, a series of nitrogen mustard derivatives of chromone were designed and synthesised, in order to discover promising anti-breast tumour candidates. Almost all target deriv...
Streptococcus pneumoniae is an important human pathogen, being one of the most common causes of community-acquired pneumonia and otitis media. Antibiotic resistance in S. pneumoniae is an emerging problem, as it depletes our arsenal of effective drugs. In addition, persistence also contributes to the antibiotic crisis in many other pathogens, yet f...
