Tsypes, Aliona Owens, Max Gibb, Brandon E
Published in
Biological psychiatry. Cognitive neuroscience and neuroimaging
The present study aimed to objectively examine the Research Domain Criteria (RDoC) subconstructs of reward anticipation and initial response to reward in adult suicide attempters, compared with nonattempters, using electroencephalography (EEG) and event-related potentials (ERPs) within the context of the RDoC-recommended experimental paradigms for ...
Vargas-Gastélum, Lluvia Riquelme, Meritxell
Published in
Life (Basel, Switzerland)
The deep sea (>1000 m below sea level) represents one of the most extreme environments of the ocean. Despite exhibiting harsh abiotic conditions such as low temperatures, high hydrostatic pressure, high salinity concentrations, a low input of organic matter, and absence of light, the deep sea encompasses a great fungal diversity. For decades, most ...
Losert, Ariane Sander, Christian Schredl, Michael Heilmann-Etzbach, Ivonne Deuschle, Michael Hegerl, Ulrich Schilling, Claudia
Published in
Brain Sciences
Central nervous hyperarousal is as a key component of current pathophysiological concepts of chronic insomnia disorder. However, there are still open questions regarding its exact nature and the mechanisms linking hyperarousal to sleep disturbance. Here, we aimed at studying waking state hyperarousal in insomnia by the perspective of resting-state ...
Seok, Darsol Smyk, Nathan Jaskir, Marc Cook, Philip Elliott, Mark Girelli, Tommaso Scott, J. Cobb Balderston, Nicholas Beer, Joanne Stock, Janet
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Published in
NeuroImage : Clinical
Disparate diagnostic categories from the Diagnostic and Statistical Manual of Mental Disorders (DSM), including generalized anxiety disorder, major depressive disorder and post-traumatic stress disorder, share common behavioral and phenomenological dysfunctions. While high levels of comorbidity and common features across these disorders suggest sha...
Sengupta, Sarojini M Grizenko, Natalie Fortier, Marie-Ève Ter-Stepanian, Marina Joober, Ridha
Published in
Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent
Ces résultats suggèrent qu’un phénotypage profond et une réduction de l’hétérogénéité peuvent être impératifs afin de découvrir « l’héritabilité manquante » du trouble.
Medeiros, Gustavo C Rush, A John Jha, Manish Carmody, Thomas Furman, Jennifer L Czysz, Andrew H Trombello, Joseph M Cooper, Crystal M Trivedi, Madhukar H
Published in
Depression and anxiety
Heterogeneity in major depressive disorder (MDD) is well recognized but not well understood. Core depressive features are reward and emotional symptoms, which reflect dysfunctions in the positive valence (PV) and negative valence (NV) systems, respectively. This study assessed whether PV and NV systems (based on selected symptoms) were associated w...
Albert, Avery B Wagner, Kayla E Van Orman, Sarah E Anders, Kristin M Forken, Patricia J Blatt, Steven D Fremont, Wanda P Faraone, Stephen V Glatt, Stephen J
Published in
Psychiatry research
The Research Domain Criteria (RDoC) initiative of the National Institute of Mental Health (NIMH) established a dimensional framework for understanding psychiatric constructs. Initial Responsiveness to Reward Attainment (IRRA) was identified as a dimensional construct relevant to several psychiatric disorders. The current study aimed to (1) examine ...
Kavanaugh, Brian C Cancilliere, Mary Kathryn Spirito, Anthony
Published in
CNS spectrums
Neurocognition is one of the strongest predictors of clinical and functional outcomes across the spectrum of psychopathology, yet there remains a dearth of unified neurocognitive nosology and available neurocognition-targeted interventions. Neurocognitive deficits manifest in a transdiagnostic manner, with no psychiatric disorder uniquely affiliate...
Crane, Natania A Vergés, Alvaro Kamali, Masoud Bhaumik, Runa Ryan, Kelly A Marshall, David F Saunders, Erika F H Kassel, Michelle T Weldon, Anne L McInnis, Melvin G
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Published in
Assessment
Trait markers, or intermediate phenotypes linking different units of analysis (self-report, performance) from the Research Domain Criteria (RDoC) matrix across populations is a necessary step in identifying at-risk individuals. In the current study, 150 healthy controls (HC) and 456 individuals with bipolar disorder (BD) Type I or II, NOS (not othe...
Levchenko, Anastasia Nurgaliev, Timur Kanapin, Alexander Samsonova, Anastasia Gainetdinov, Raul R.
Published in
Heliyon
Neuroscience; Bioinformatics; Genetics; Pharmaceutical Science; Molecular Biology; Pathophysiology; Mathematical Biosciences; Psychiatry; Evidence-Based Medicine; Biomarker; human brain; Machine Learning; Pharmacotherapy; RDoC; schizophrenia
