Haining, Brianna
Most cultures obtain the majority of their caloric and mineral nutrition from cereals either directly or through livestock; therefore, understanding the genetic architecture underlying the acquisition of ions from the soil in these crops is important for agricultural purposes. The ionome of an organism is intricately interconnected; many transporte...
Lusk, Ryan Saba, Laura M Vanderlinden, Lauren A Zidek, Vaclav Silhavy, Jan Pravenec, Michal Hoffman, Paula L Tabakoff, Boris
Published in
Alcoholism, clinical and experimental research
A statistical pipeline was developed and used for determining candidate genes and candidate gene coexpression networks involved in 2 alcohol (i.e., ethanol [EtOH]) metabolism phenotypes, namely alcohol clearance and acetate area under the curve in a recombinant inbred (RI) (HXB/BXH) rat panel. The approach was also used to provide an indication of ...
Hall, Rabea A Lammert, Frank
Published in
Methods in molecular biology (Clifton, N.J.)
This systems genetics analysis comprises quantitative measurements of hepatic fibrogenesis in mouse models and mapping of quantitative traits in mouse genetic reference populations. It is part of a large mapping project of fibrogenic genes including the analyses of experimental crosses from different inbred mouse strains. Extensive quantitative tra...
Zhang, Dan Zhang, Hengyou Chu, Shanshan Li, Hongyan Chi, Yingjun Triebwasser-Freese, Daniella Lv, Haiyan Yu, Deyue
Published in
Plant Molecular Biology
Soybean is a high phosphorus (P) demand species that is sensitive to low-P stress. Although many quantitative trait loci (QTL) for P efficiency have been identified in soybean, but few of these have been cloned and agriculturally applied mainly due to various limitations on identifying suitable P efficiency candidate genes. Here, we combined QTL ma...
Liu, Hongjun Niu, Yongchao Gonzalez-Portilla, Pedro J. Zhou, Huangkai Wang, Liya Zuo, Tao Qin, Cheng Tai, Shuaishuai Jansen, Constantin Shen, Yaou
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Published in
BMC Genomics
BackgroundTo safeguard the food supply for the growing human population, it is important to understand and exploit the genetic basis of quantitative traits. Next-generation sequencing technology performs advantageously and effectively in genetic mapping and genome analysis of diverse genetic resources. Hence, we combined re-sequencing technology an...
Jiang, Yun-Feng Wang, Ji-Rui Luo, Wei Wei, Yu-Ming Qi, Peng-Fei Liu, Ya-Xi Jiang, Qian-Tao Peng, Yuan-Ying Chen, Guo-Yue Dai, Shou-Fen
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Published in
Euphytica
Tibetan semi-wild wheat (Triticum aestivum ssp. tibetanum Shao) is a hexaploid wheat resource distributed only in Tibet that has an interesting type of seed dormancy in addition to hulled glumes and brittle spikelets. A whole-genome linkage map of T. aestivum ssp. tibetanum was constructed for a population of 186 recombinant inbred lines using 645 ...
Poon, Anna Goldowitz, Daniel
Published in
BMC Genomics
BackgroundAdult neurogenesis, which is the continual production of new neurons in the mature brain, demonstrates the strikingly plastic nature of the nervous system. Adult neural stem cells and their neural precursors, collectively referred to as neural progenitor cells (NPCs), are present in the subgranular zone (SGZ) of the dentate gyrus, the sub...
Wisser, Kathleen C. Schauerte, Joseph A. Burke, David T. Galecki, Andrzej Chen, Shu Miller, Richard A. Gafni, Ari
Published in
Archives of Biochemistry and Biophysics
Biophysical measurements indicative of protein stability and function were performed on crude extracts from liver, muscle, and lens of a genetically heterogeneous mouse population. Genetic information was used to search for quantitative trait loci (QTL) that influenced the biophysical traits, with emphasis on phenotypes that previously have been sh...