Giagnorio, Roberto Hansmann, Georg
Published in
Cardiovascular Diagnosis and Therapy
Bronchopulmonary dysplasia (BPD) is a combined pulmonary vascular and parenchymal disease, representing the most common cause of chronic lung disease (CLD) in infancy. Pulmonary hypertension (PH) is frequently associated with BPD and—if persistent—substantially increases mortality. We report on a 4-month-old, former preterm infant with BPD, severe ...
Truong, Uyen Meinel, Katharina Haddad, Francois Koestenberger, Martin Carlsen, Jørn Ivy, Dunbar Jone, Pei-Ni
Published in
Cardiovascular Diagnosis and Therapy
Pulmonary hypertension (PH) is a progressive disease affecting patients across the life span. The pathophysiology primarily involves the pulmonary vasculature and right ventricle (RV), but eventually affects the left ventricular (LV) function as well. Safe, accurate imaging modalities are critical for diagnosis, serial monitoring, and tailored ther...
Andersen, Asger van der Feen, Diederik E. Andersen, Stine Schultz, Jacob Gammelgaard Hansmann, Georg Bogaard, Harm Jan
Published in
Cardiovascular Diagnosis and Therapy
Right heart failure may be the ultimate cause of death in patients with acute or chronic pulmonary hypertension (PH). As PH is often secondary to other cardiovascular diseases, the treatment goal is to target the underlying disease. We do however know, that right heart failure is an independent risk factor, and therefore, treatments that improve ri...
Louise, Bacon Jenny Carys, Fleming Philip, Marino
Published in
Journal of Thoracic Disease
Pulmonary hypertension (PH) is a condition of raised pulmonary artery pressure (PAP), which may be secondary to a number of causes, one of which is sleep disordered breathing (SDB). When PH complicates SDB, it carries a significant burden of morbidity and mortality due to the risk of progression to right ventricular failure over time. This narrativ...
Zeng, Xiaomei Chen, Haiming Ruan, Honglian Ye, Xiaojuan Li, Jieying Hong, Cheng
Published in
Journal of Thoracic Disease
Background Pulmonary hypertension (PH) is a chronic progressive disease characterized by increasing pulmonary vascular resistance, poor prognosis and high disability rate. Although many targeted drugs for PH have been put to clinical use, most patients still have poor exercise tolerance and quality of life. Exercise training is considered to furthe...
Edmonston, Daniel L Parikh, Kishan S Rajagopal, Sudarshan Shaw, Linda K Abraham, Dennis Grabner, Alexander Sparks, Matthew A Wolf, Myles
Published in
American journal of kidney diseases : the official journal of the National Kidney Foundation
Pulmonary hypertension (PH) contributes to cardiovascular disease and mortality in patients with chronic kidney disease (CKD), but the pathophysiology is mostly unknown. This study sought to estimate the prevalence and consequences of PH subtypes in the setting of CKD. Observational retrospective cohort study. We examined 12,618 patients with a rig...
Dzudie, Anastase Dzekem, Bonaventure Suiru Ojji, Dike B Kengne, Andre Pascal Mocumbi, Ana Olga Sliwa, Karen Thienemann, Friedrich
Published in
Cardiovascular diagnosis and therapy
Pulmonary hypertension (PH) is a devastating, progressive disease with increasingly debilitating symptoms and usually shortened overall life expectancy. This article reviews the global epidemiology of PH with focus on low- and middle-income countries (LMICs) and sub-Sahara African in particular. Although left ventricular heart disease is the most c...
Liu, Bing-Yang Wu, Wei-Chun Zeng, Qi-Xian Liu, Zhi-Hong Niu, Li-Li Tian, Yue Cheng, Xiao-Ling Luo, Qin Zhao, Zhi-Hui Huang, Li
...
Published in
Annals of Translational Medicine
Background Right ventricular (RV) intraventricular mechanical dyssynchrony detected by two-dimensional speckle tracking echocardiography (2D-STE) has been reported to be correlated with a decrease in RV contractile efficiency in pulmonary hypertension (PH) patients, while little attention has been paid to biventricular dysfunction. Therefore, we ai...
Purga, Scott L. Karas, Maria G. Horn, Evelyn M. Torosoff, Mikhail T.
Published in
Journal of Echocardiography
BackgroundThe contribution of progressive left atrial (LA) enlargement to elevated pulmonary capillary wedge pressure (PCWP) in patients with WHO Group II pulmonary hypertension (PH) has not been well studied. We hypothesized that progressive LA enlargement is associated with increased PCWP.MethodsA cross-sectional retrospective cohort consisted of...
Beaudoin, Jonathan Szymonifka, Jackie Lavender, Zachary Deaño, Roderick C. Zhou, Qing Januzzi, James L. Singh, Jagmeet P. Truong, Quynh A.
Published in
Journal of Thoracic Disease
Background Pulmonary hypertension (PH) is an adverse prognostic marker in patients undergoing cardiac resynchronization therapy (CRT). We sought to determine the relation of biomarkers of fibrosis [soluble ST2 (sST2), galectin-3], wall stretch [amino terminal pro-brain natriuretic peptide (NT-proBNP)], and necrosis [high-sensitivity troponin-I (hsT...
