Zahorska, Eva Rosato, Francesca Stober, Kai Kuhaudomlarp, Sakonwan Meiers, Joscha Hauck, Dirk Reith, Dorina Gillon, Emilie Rox, Katharina Imberty, Anne
...
Published in
Angewandte Chemie (International ed. in English)
Bacterial adhesion, biofilm formation and host cell invasion of the ESKAPE pathogen Pseudomonas aeruginosa require the tetravalent lectins LecA and LecB, which are therefore drug targets to fight these infections. Recently, we have reported highly potent divalent galactosides as specific LecA inhibitors. However, they suffered from very low solubil...
Mohammed, H Mather, M W Lumb, J Butler, C C Wilson, J A
Published in
The Journal of laryngology and otology
Otitis externa accounts for 1.1-1.3 per cent of patient presentations in primary care and 25 per cent of urgent referrals to ENT. This study aimed to explore otitis externa clinical decision-making at the primary-secondary care interface, otitis externa prevalence and recent trends in antimicrobial resistance in otitis externa related bacterial iso...
Burghard, Marcella Takken, Tim Nap-van der Vlist, Merel M Nijhof, Sanne L van der Ent, C Kors Heijerman, Harry G M Hulzebos, H J Erik
Published in
Therapeutic advances in respiratory disease
[1] To investigate the cardiorespiratory fitness (CRF) levels in children and adolescents with cystic fibrosis (CF) with no ventilatory limitation (ventilatory reserve ⩾ 15%) during exercise, and [2] to assess which physiological factors are related to CRF. A cross-sectional study design was used in 8- to 18-year-old children and adolescents with C...
Aziz, Farooq Rashid, Muhammad Rehman, Mubashar Rafique, Muhammad Imran, Muhammad
Published in
Combinatorial chemistry & high throughput screening
The aim of the study is to develop advanced antibacterial agents as nanoparticles instead of antibiotics due to the emergence of antimicrobial resistance. Pseudomonas aeruginosa is capable of causing many diseases, including serious bacterial pneumonia. There is a need for an efficient antibacterial agent to kill these pathogens. The objective of t...
Jasim, B H Ali, E H
Published in
Archives of Razi Institute
Pseudomonas aeruginosa was isolated from injuries of patients' wounds and burns, and to ensure that the isolate was belonging to P. aeruginosa, several tests were performed, such as staining techniques, a biochemical test, morphological test, Vitek 2 system, and sensitivity test. The results of the gram stain test showed rod pink gram-negative bact...
Ishchenko, O.V. Stepanskyi, D.O.
Published in
Medicni perspektivi (Medical perspectives)
The purpose of the study was to determine the frequency rate of Pseudomonas aeruginosa infection among children with cystic fibrosis (CF) in Dnipro region and to provide microbiological characteristics of the obtained isolates. The study was conducting from January 2019 to December 2020. Children with genetically confirmed CF diagnosis were enrolle...
Daradkeh, Salah Tewfik Abunasser, Mohammad Jamal Daradkeh, Yazan Tawfiq Olimat, Mohammad Suleiman Dabbas, Waleed F Akel, Alaa
Published in
International journal of surgery case reports
Septic knee arthritis after elective arthroscopic procedures is a rare surgical emergency, with Pseudomonas aeruginosa even more rarely causing the infection. The treatment by arthroscopic debridement and lavage with diluted Povidone-Iodine has potential benefits that may be useful in improving the prognosis for patients. This case report discusses...
Shah, Ruchi Amador, Cynthia Tormanen, Kati Ghiam, Sean Saghizadeh, Mehrnoosh Arumugaswami, Vaithi Kumar, Ashok Kramerov, Andrei A Ljubimov, Alexander V
Published in
Experimental eye research
There is a number of systemic diseases affecting the cornea. These include endocrine disorders (diabetes, Graves' disease, Addison's disease, hyperparathyroidism), infections with viruses (SARS-CoV-2, herpes simplex, varicella zoster, HTLV-1, Epstein-Barr virus) and bacteria (tuberculosis, syphilis and Pseudomonas aeruginosa), autoimmune and inflam...
Bavaro, Davide Fiore Romanelli, Federica Stolfa, Stefania Belati, Alessandra Diella, Lucia Ronga, Luigi Fico, Cecilia Monno, Laura Mosca, Adriana Saracino, Annalisa
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Published in
Infectious diseases (London, England)
Cefiderocol is a new siderophore cephalosporin designed to be active against extensively resistant Gram-negative bacteria; however, clinical studies are limited to complicated urinary tract infections, pneumonia, and intra-abdominal infections. To date, no data are available on neurosurgical site infections. We present a case of a patient successfu...
Sànchez Marrè, Miquel Mora Jiménez, Inmaculada Soguero Ruiz, Cristina Martínez Agüero, Sergio Álvarez Rodríguez, Joaquín Hernàndez Carnerero, Àlvar
One threatening medical problem for human beings is the increasing antimicrobial resistance of some microorganisms. This problem is especially difficult in Intensive Care Units (ICUs) of hospitals due to the vulnerable state of patients. Knowing in advance whether a concrete bacterium is resistant or susceptible to an antibiotic is a crux step for ...