Yaron, Jordan R Zhang, Liqiang Burgin, Michelle Schutz, Lauren N Awo, Enkidia A Keinan, Shahar McFadden, Grant Ambadapadi, Sriram Guo, Qiuyun Chen, Hao
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Published in
Methods in molecular biology (Clifton, N.J.)
Viruses have devised highly effective approaches that modulate the host immune response, blocking immune responses that are designed to eradicate viral infections. Over millions of years of evolution, virus-derived immune-modulating proteins have become extraordinarily potent, in some cases working at picomolar concentrations when expressed into su...
ALMEIDA, F. da S. MINGOTTE, F. L. C. COELHO, A. P. LEMOS, L. B. SANTANA, M. J. de ROCHA, M. de M.
The aim of the present study was to evaluate whether the sowing period changes the grain technological quality of cowpea cultivars and to indicate which of these have the highest technological quality when grown in the Center-South region of Brazil. The experiment was conducted in a randomized block design, with a 6 x 3 factorial arrangement, using...
Liu, Jiang Ding, Xin Fu, Yupeng Xiang, Cen Yuan, Yuan Zhang, Yongmin Yu, Peng
Published in
European journal of medicinal chemistry
Macro biomolecules are of vital importance in regulating the biofunctions in organisms, in which proteins (including peptides when mentioned below) and nucleic acids (NAs) are the most important. Therefore, these proteins and NAs can be applied as "drugs" to regulate the biofunctions from abnormal to normal. Either for proteins and NAs, the most ch...
Zhong, Cuiling Li, Pin Argade, Sulabha Liu, Lixian Chilla', Anastasia Liang, Wei Xin, Hong Eliceiri, Brian Choudhury, Biswa Ferrara, Napoleone
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Endothelial cell (EC) metabolism is thought to be one of the driving forces for angiogenesis. Here we report the identification of the hexosamine D-mannosamine (ManN) as an EC mitogen and survival factor for bovine and human microvascular EC, with an additivity with VEGF. ManN inhibits glycosylation in ECs and induces significant changes in N-glyca...
Stepler, Kaitlyn E Mahoney, Emily R Kofler, Julia Hohman, Timothy J Lopez, Oscar L Robinson, Renã A S
Published in
Neurobiology of disease
Alzheimer's disease (AD) disproportionately affects certain racial and ethnic subgroups, such as African American/Black and Hispanic adults. Genetic, comorbid, and socioeconomic risk factors contribute to this disparity; however, the molecular contributions have been largely unexplored. Herein, we conducted a pilot proteomics study of postmortem br...
Pietzner, Maik Wheeler, Eleanor Carrasco-Zanini, Julia Raffler, Johannes Kerrison, Nicola D Oerton, Erin Au Yeung, Victoria Luan, Jian'an Finan, Chris Casas, Juan P
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Understanding the genetic architecture of host proteins interacting with SARS-CoV-2 or mediating the maladaptive host response to COVID-19 can help to identify new or repurpose existing drugs targeting those proteins. We present a genetic discovery study of 179 such host proteins among 10,708 individuals using an aptamer-based technique. We identif...
Rodrigues, Isabella C P Pereira, Karina D Freire Woigt, Luiza Jardini, André L Luchessi, Augusto D Lopes, Éder S N Webster, Thomas J Gabriel, Laís P
Published in
Artificial organs
Tubular polymer scaffolds based on tissue engineering techniques have been studied as potential alternatives for vascular regeneration implants. The blood vessels of the cardiovascular system are mainly fibrous, composed of collagen (Col) and elastin (El), and its inner layer consists of endothelial cells. In this work, Col and El were combined wit...
MAZONI, I. NESHICH, G.
Introdução. Nanoambientes proteicos e suas características. Lista dos descritores físico-químicos e estruturais que caracterizam os nanoambientes específicos. Contribuições. Qual é o significado do conhecimento sobre os nanoambientes proteicos. Um dicionário dos descritores dos nanoambientes terá impacto na variedade de pesquisas que visam a inovaç...
Tóthová, Csilla Karasová, Martina Blaňarová, Lucia Fialkovičová, Mária Nagy, Oskar
Published in
Scientific Reports
Canine babesiosis may cause several hematological and biochemical changes, but only limited studies are available regarding the possible differences of changes in animals infected by different Babesia parasites. The study focused on the evaluation of the differences in serum protein electrophoretic pattern between dogs naturally infected with B. gi...
Zhu, Chao Wang, Huiqin Ma, Hongrui Yang, Yonglin Li, Fan
Published in
Environmental science and pollution research international
Humic-like substances are essential components of soluble organic matter in tannery wastewater. However, the tannery process can promote the abiotic humification in wastewater. Therefore, it is of great significance to clarify the pathway and degree of abiotic humification and the properties of the as-derived humic acid-like (HAL) complex polymers ...
