Eroukhmanoff, J. Tejedor, I. Potorac, Iulia Cuny, T. BONNEVILLE, Jean-François Dufour, H. Weryha, G. Beckers, Albert Touraine, P. Brue, T.
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peer reviewed / OBJECTIVE: Both antitumor and antisecretory efficacies of dopamine agonists (DA) make them the first-line treatment of macroprolactinomas. However, there is no guideline for MRI follow-up once prolactin is controlled. The aim of our study was to determine whether a regular MRI follow-up was necessary in patients with long-term norma...
Salenave, Sylvie Ancelle, Deborah Bahougne, Thibaut Raverot, Gérald Kamenický, Peter Bouligand, Jérôme Guiochon-Mantel, Anne Linglart, Agnès Souchon, Pierre-François Nicolino, Marc
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Published in
The Journal of clinical endocrinology and metabolism
Pituitary adenomas are rare in children and adolescents. The response of macroprolactinomas to dopamine agonists (DA) in this age group has been less extensively studied than in adults. We retrospectively analyzed data on a large cohort of young patients with macroprolactinomas. Patients aged younger than 20 years at macroprolactinoma diagnosis and...
Sliwa, Karen Blauwet, Lori Tibazarwa, Kemi Libhaber, Elena Smedema, Jan*-Peter Becker, Anthony McMurray, John Yamac, Hatice Labidi, Saida Struman, Ingrid
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peer reviewed / BACKGROUND: Peripartum cardiomyopathy (PPCM) is a potentially life-threatening heart disease that occurs in previously healthy women. We identified prolactin, mainly its 16-kDa angiostatic and proapoptotic form, as a key factor in PPCM pathophysiology. Previous reports suggest that bromocriptine may have beneficial effects in women ...
Tamagno, Gianluca Daly, Adrian Deprez, Manuel Vroonen, Laurent Andris, Cécile Martin, Didier Beckers, Albert
Introduction L’impuissance sexuelle et la diminution de libido sont les symptômes principaux du prolactinome chez l’homme. Nous décrivons un cas inhabituel sur les plans clinique, anatomopathologique et biologique chez un homme souffrant d’un prolactinome géant mais gardant une fonction gonadique normale. Cas clinique Un homme de 57 ans s’est prése...
Tamagno, Gianluca Daly, Adrian Deprez, Manuel Vroonen, Laurent Andris, Cécile Martin, Didier Beckers, Albert
Introduction L’impuissance sexuelle et la diminution de libido sont les symptômes principaux du prolactinome chez l’homme. Nous décrivons un cas inhabituel sur les plans clinique, anatomopathologique et biologique chez un homme souffrant d’un prolactinome géant mais gardant une fonction gonadique normale. Cas clinique Un homme de 57 ans s’est prése...
Pitchot, William Hansenne, Michel Pinto, Emmanuel Reggers, Jean Fuchs, Sonia Ansseau, Marc
peer reviewed / BACKGROUND: Several lines of evidence suggest a clear relationship between serotonin (5-hydroxytryptamine, 5-HT) hypoactivity and suicidal behavior across several psychiatric diagnoses. Few data are available, however, regarding the possible specific role of 5-HT1A receptors in the biology of suicidality. Therefore, the aim of our s...
Valdes Socin, Hernan Gonzalo Chanson, Philippe Delemer, B. Tabarin, A. Rohmer, V. Mockel, J. Stevenaert, Achille Beckers, Albert
peer reviewed / OBJECTIVE: Our aim was to report the recent changes in diagnosis and management of TSH-secreting pituitary adenomas. METHODS: We retrieved 43 consecutive patients with TSH-secreting pituitary tumors (23 male and 20 female) among 4400 pituitary adenomas followed between 1976 and 2001 in six Belgian and French centers. RESULTS: TSH wa...
Hansenne, Michel Pitchot, William Pinto, Emmanuel Reggers, Jean Scantamburlo, Gabrielle Fuchs, S. Pirard, S. Ansseau, Marc
peer reviewed / BACKGROUND: A number of challenge studies have reported abnormalities of serotonergic function in borderline personality disorder (BPD). There are, however, problems with the pharmacological probes used in these studies since fenfluramine and m-CPP are not only serotonergic agents but also induce release of catecholamines, particula...
Pitchot, William Ansseau, Marc Gonzalez Moreno, Antonio Hansenne, Michel
peer reviewed
Beckers, Albert Abs, R. Mahler, C. Vandalem, J. L. Pirens, G. Hennen, Georges Stevenaert, Achille
peer reviewed / Seven patients with hyperthyroidism due to a TSH-secreting pituitary macroadenoma have been observed of a total of 800 patients with pituitary tumors over a period of 15 yr. Serum TSH levels varied between 1.1-36.3 mU/L. The serum alpha-subunit level was low in 1 case, while in 4 other cases the concentration was elevated and varied...