Dong, Meng-Ya Xu, Chen-Bo Zhang, Li-Sha Deng, Fu-Xue Zhang, Zhan-Yi Shu, Shan Yuan, Zu-Yi Zhou, Juan
Published in
Medicina clinica
Atrial fibrillation (AF) has the close relation to thyroid dysfunction and these two diseases lead to poor cardiovascular outcomes. But the prognostic value of thyroid diseases in AF remains unclear. We aimed to determine whether history of thyroid diseases is associated with risk of in-hospital cardiovascular outcomes in AF. Based on the data from...
Lin, Jian-Xian Yoon, Changhwan Li, Ping Yu, Qian Qiu, Sheng-Liang Zheng, Chao-Hui Yoon, Sam S Huang, Chang-Ming
Published in
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract
We have shown that activation of the receptor tyrosine kinase (RTK)-RAS pathway in gastric adenocarcinoma (GA) promotes acquisition of cancer stem-like cell (CSC) phenotypes including metastasis and chemotherapy resistance. Here, we evaluated the prognostic value of the CSC marker CD44 and the RTK-RAS activation marker phosphorylated MEK (p-MEK) in...
Oyake, Kazuaki Otaka, Yohei Matsuura, Daisuke Honaga, Kaoru Mori, Naoki Kondo, Kunitsugu
Published in
Archives of physical medicine and rehabilitation
To determine whether poststroke fatigue at admission is associated with the degree of independence in activities of daily living in patients with stroke at discharge from subacute rehabilitation wards. Retrospective cohort study. Subacute rehabilitation hospital. A consecutive sample of patients (N=156) with stroke who were admitted to a subacute r...
Lebkuchen, Adriana Freitas, Lunara S Cardozo, Karina H M Drager, Luciano F
Published in
Trends in cardiovascular medicine
Obstructive sleep apnea (OSA) is a common clinical condition associated with increased cardiovascular morbidity and mortality. Recent evidence from clinical studies and animal models suggest that OSA can promote cardiovascular disease by inducing autonomic, hemodynamic, inflammatory and metabolic dysregulation. However, most of the evidence address...
Manabe, Shun Kataoka, Hiroshi Mochizuki, Toshio Iwadoh, Kazuhiro Ushio, Yusuke Kawachi, Keiko Watanabe, Kentaro Watanabe, Saki Akihisa, Taro Makabe, Shiho
...
Published in
Journal of atherosclerosis and thrombosis
We aimed to examine the association between the maximum intima-media thickness of the carotid artery (Max IMT) and renal prognosis, considering their potential interaction with age. Survival analyses were performed in 112 patients with chronic kidney disease (CKD), to assess renal prognosis, with the endpoint defined as a ≥ 30% decline in estimated...
Lee, Shirley H. F. Abdul Rahman, Hanif Abidin, Nadiah Ong, Sok King Leong, Elvynna Naing, Lin
Published in
BMC Cancer
BackgroundColorectal cancer (CRC) is a major cause of cancer-related mortality worldwide. It is the second leading cause of cancer death in men and women in Brunei Darussalam in 2017, posing a major burden on society.MethodsThis retrospective cohort study (n = 1035 patients diagnosed with CRC in Brunei Darussalam from 1st January 2002 until 31st De...
Zheng, Fangchao Du, Feng Qian, Haili Zhao, Jiuda Wang, Xue Yue, Jian Hu, Nanlin Si, Yiran Xu, Binghe Yuan, Peng
...
Published in
Biomarker Research
BackgroundN6-methyladenosine(m6A) methylation modification affects the tumorigenesis, progression, and metastasis of breast cancer (BC). However, the expression characteristics and prognostic value of m6A modification in BC are still unclear. We aimed to evaluate the relationship between m6A modification and clinicopathological characteristics, and...
Li, Jun Ge, Zheng
Published in
BMC Cancer
BackgroundAcute myeloid leukemia (AML) remains one of the most common hematological malignancies, posing a serious challenge to human health. HSPA8 is a chaperone protein that facilitates proper protein folding. It contributes to various activities of cell function and also is associated with various types of cancers. To date, the role of HSPA8 in ...
Gladman, Dafna D.
Published in
Current Rheumatology Reports
Purpose of ReviewTo review current understanding of the prevalence, clinical features, outcome measures and recent therapeutic trials in axial psoriatic arthritis (axPsA).Recent FindingsThe prevalence of axPsA is estimated at 40–50%. However, the definition of axPsA remains unclear, therefore these estimates may be inaccurate. Ax PsA appears to be ...
Kong, Weihao Yang, Mingwei Zhang, Jianfeng Cheng, Ya Dai, Tianxing Zhang, Jian Wang, Guoying Zhang, Jianlin
Published in
BMC Cancer
BackgroundAs is well recognized that inflammation plays a crucial role in the genesis and progression of various cancer. Here we investigate the prognostic value of a novel index: the combination of neutrophil to lymphocyte ratio and platelet distribution width (coNLR-PDW) in post-operation patients with resectable hepatocellular carcinoma (HCC).Me...
