Getachew, Hallelujah Demissew, Assalif Abossie, Ashenafi Habtamu, Kassahun Wang, Xiaoming Zhong, Daibin Zhou, Guofa Lee, Ming-Chieh Hemming-Schroeder, Elizabeth Bradley, Lauren
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BACKGROUND: Water resource development projects, such as dams and irrigation schemes, have a positive impact on food security and poverty reduction. However, such projects could increase prevalence of vector borne disease, such as malaria. This study investigate the impact of different agroecosystems and prevalence of malaria infection in Southwest...
Brownell, Kristy Friebur, Robin Perera, Rachel Brown, Erika Mayer, Stefanie Feng, Ingrid Clermont, Sabrina Ritchie, Lorrene Epel, Elissa Laraia, Barbara
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PURPOSE: The National Heart, Lung and Blood Institute Growth and Health Study (NGHS) prospectively collected anthropometric, biospecimens, clinical, health behaviour and psychosocial measures associated with cardiovascular disease from childhood to young adulthood. The aim of the current study was to assess the impact of stress, dysregulated eating...
Mo, Jonathan Sharma, Julia Darrow, Morgan
BACKGROUND: Langerhans cell histiocytosis (LCH) is a neoplastic transformation of myeloid precursors that commonly presents as an osteolytic lesion of the long or flat bones in children. Aneurysmal bone cysts (ABC) are benign neoplasms that frequently affect the metaphysis of long bones and the spine, often revealing a rapidly expansile lesion with...
Kashef, Shabnam Bell, Lucinda K Brown, Victoria Gardner, Claire Zarnowiecki, Dorota Morgillo, Samantha Arguelles, Jennifer C Cox, David N Golley, Rebecca K
Published in
Public health nutrition
To evaluate the impact of a menu box delivery service tailored to the long day care (LDC) setting on improving menu compliance with recommendations, children's diet quality and dietary intake while in care. A cluster randomised controlled trial in LDC centres randomly assigned to an intervention (menu box delivery) or comparison (menu planning trai...
Larsen, Liva Bundgaard Daley, David Lange, Anne-Mette Sonuga-Barke, Edmund Thomsen, Per Hove Jensen, Jens Søndergaard Rask, Charlotte Ulrikka
Published in
European child & adolescent psychiatry
Children with attention-deficit/hyperactivity disorder (ADHD) can be more stress-vulnerable, and thereby, it has been suggested, prone to develop functional somatic symptoms (FSS) compared to their peers. In this paper, using data from 160 children aged 3-7 years with ADHD from the D'SNAPP study, a randomized controlled trial testing a parent train...
Chandasana, Hardik Thapar, Mita Hayes, Siobhan Baker, Mark Gibb, Diana Turkova, Anna Ford, Deborah Wiznia, Andrew Fairlie, Lee Bwakura-Dangarembizi, Mutsa
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BACKGROUND AND OBJECTIVE: HIV treatment options remain limited in children. Dolutegravir is a potent and well-tolerated, once-daily HIV-1 integrase inhibitor recommended for HIV-1 infection in both adults and children down to 4 weeks of age. To support pediatric dosing of dolutegravir in children, we used a population pharmacokinetic model with dol...
Overgaard, Kristin Romvig Oerbeck, Beate Friis, Svein Pripp, Are Hugo Aase, Heidi Biele, Guido Ingeborgrud, Christine Baalsrud Polanczyk, Guilherme V Zeiner, Pål
Published in
European child & adolescent psychiatry
Identifying attention-deficit/hyperactivity disorder (ADHD) in pre-schoolers may improve their development if treated, but it is unclear whether ADHD symptoms from this age are stable enough to merit treatment. We aimed to investigate the stability of parent- and teacher-reported ADHD symptoms and ADHD classified above the diagnostic symptom thresh...
Stevenson, Morgan Bieri, Gregor Kaletsky, Rachel St Ange, Jonathan Remesal, L Pratt, Karishma Zhou, Shiyi Weng, Yifei Murphy, Coleen Villeda, Saul
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Loss of cognitive function with age is devastating. EGL-30/GNAQ and Gαq signaling pathways are highly conserved between C. elegans and mammals, and murine Gnaq is enriched in hippocampal neurons and declines with age. We found that activation of EGL-30 in aged worms triples memory span, and GNAQ gain of function significantly improved memory in age...
Midgette, Allegra Ma, Danyang Stowe, Lucy Chernyak, Nadia
Across many cultural contexts, the majority of women conduct the majority of their household labor. This gendered distribution of labor is often unequal, and thus represents one of the most frequently experienced forms of daily inequality because it occurs within ones own home. Young children are often passive observers of their familys distributio...
Rzehak, Peter Grote, Veit Langhendries, Jean-Paul Verduci, Elvira Ferre, Natalia Gruszfeld, Darek Gao, Lu Guan, Weihua Zeng, Xuehuo Schisterman, Enrique
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BACKGROUND: Seasonal variations in environmental exposures at birth or during gestation are associated with numerous adult traits and health outcomes later in life. Whether DNA methylation (DNAm) plays a role in the molecular mechanisms underlying the associations between birth season and lifelong phenotypes remains unclear. METHODS: We carried out...