Peer, Sameer Nagaraj, Chandana Mangalore, Sandhya
Published in
Egyptian Journal of Radiology and Nuclear Medicine
BackgroundThe association of tuberculosis and motor neuron disease-like illness has not been described previously. We present a case of co-existent pulmonary and extra-pulmonary tuberculosis in a young man whose clinical presentation was suggestive of a motor neuron disease-like illness and was subsequently diagnosed with tubercular infection. This...
Han, Sangwon Oh, Jungsu S Kim, Jae Seung
Published in
Annals of nuclear medicine
A comprehensive understanding of the link between 18F-FDG PET/CT and the tumor immune microenvironment (TIM) is lacking. We, therefore, investigated the TIM in regard to the gene signature of 18F-FDG PET/CT in head and neck squamous cell carcinoma (HNSC). The mRNA sequence data of 480 HNSC patients on The Cancer Genome Atlas portal were used to exp...
Lee, Hwan Eads, Jennifer R Pryma, Daniel A
Published in
The oncologist
Somatostatin analogs (SSAs) are the frontline antitumor therapy in advanced well-differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NETs). A subset of patients demonstrate early disease progression on SSA therapy, yet the currently known predictors for treatment failure lack specificity to affect therapeutic decision. SSAs target tumo...
Nomura, Masahiko Toyama, Hiroshi Suzuki, Hiromi Yamada, Takashi Hatano, Kentaro Wilson, Alan A Ito, Kengo Sawada, Makoto
Published in
Annals of nuclear medicine
The activation of microglia in various brain pathologies is accompanied by an increase in the expression of peripheral benzodiazepine receptor/18 kDa translocator protein (PBR/TSPO). However, whether activated microglia have a neuroprotective or neurotoxic effect on neurons in the brain is yet to be determined. In this study, we investigated the ab...
Connor, Martin J Dubash, Suriaya Bass, Edward J Tam, Henry Barwick, Tara Khoo, Vincent Winkler, Mathias Ahmed, Hashim U
Published in
European urology focus
Recent evidence from randomised trials supports the diagnostic superiority of prostate-specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT) over conventional imaging in the detection of distant occult metastasis in men with newly diagnosed high-risk prostate cancer. This may result in a rise in the detection ...
Teuho, Jarmo Riehakainen, Leon Honkaniemi, Aake Moisio, Olli Han, Chunlei Tirri, Marko Liu, Shihao Grönroos, Tove J. Liu, Jie Wan, Lin
...
Published in
EJNMMI Research
BackgroundWe investigated the image quality of 11C, 68Ga, 18F and 89Zr, which have different positron fractions, physical half-lifes and positron ranges. Three small animal positron emission tomography/computed tomography (PET/CT) systems were used in the evaluation, including the Siemens Inveon, RAYCAN X5 and Molecubes β-cube. The evaluation was p...
Kang, Yeona Rúa, Sandra Milena Hurtado Kaunzner, Ulrike W Perumal, Jai Nealon, Nancy Qu, Wenchao Kothari, Paresh J Vartanian, Timothy Kuceyeski, Amy Gauthier, Susan A
...
Published in
Molecular imaging and biology
The γ-aminobutyric acid (GABA) is the main inhibitory neurotransmitter and essential for normal brain function. The GABAergic system has been shown to have immunomodulatory effects and respond adaptively to excitatory toxicity. The association of the GABAergic system and inflammation in patients with multiple sclerosis (MS) remains unknown. In this...
Bauckneht, Matteo Pastorino, Fabio Castellani, Patrizia Cossu, Vanessa Orengo, Anna Maria Piccioli, Patrizia Emionite, Laura Capitanio, Selene Yosifov, Nikola Bruno, Silvia
...
Published in
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Oxidative stress and its interference on myocardial metabolism play a major role in Doxorubicin (DXR) cardiotoxic cascade. Mice models of neuroblastoma (NB) were treated with 5 mg DXR/kg, either free (Free-DXR) or encapsulated in untargeted (SL[DXR]) or in NB-targeting Stealth Liposomes (pep-SL[DXR] and TP-pep-SL[DXR]). Control mice received saline...
Roder, Constantin Haas, Patrick Fudali, Monika Milian, Monika Ernemann, Ulrike Meyer, Philipp T Tatagiba, Marcos Khan, Nadia
Published in
Neurosurgical review
Patients with moyamoya angiopathy (MMA) are known to have an increased risk of impaired executive function (dysexecutive cognitive syndrome (DCS)). Numbers of moyamoya patients with DCS vary strongly in the literature; evidence of a correlation to affected vascular territories is low. This study aims to identify cognitive impairment in adult moyamo...
Lassen, Martin Lyngby Manabe, Osamu Otaki, Yuka Eisenberg, Evann Huynh, Phi T Wang, Frances Berman, Daniel S Slomka, Piotr J
Published in
European journal of nuclear medicine and molecular imaging
Quantification of myocardial blood flow (MBF) has become central in the clinical application of Rubidium-82 (82Rb) PET myocardial perfusion scans. Current recommendations suggest injections of 1100-1500 MBq of 82Rb in bolus form, which poses a potential risk of PET system saturation on most 3D PET/CT systems currently being used. We aimed to evalua...
