Lee, Kristina G. Roy, Varun Laszlo, Meghan Atkins, Katelyn M. Lin, Katrina J. Tomassian, Shant Hendifar, Andrew E.
Published in
Current Treatment Options in Oncology
Despite extensive research that has identified new risk factors, genetic mutations, and therapeutic options, pancreatic ductal adenocarcinoma continues to be a leading cause of cancer related death. Patients with pancreatic cancer, along with their clinicians, must balance realistic hope alongside a life-threatening diagnosis. As the search for tre...
Barcelos, Samantha Thifani Alrutz Dall'Oglio, Vincent Marin de Araújo, Alexandre Cerski, Carlos Thadeu Schmidt Álvares-da-Silva, Mário Reis
Published in
Annals of hepatology
Hepatic sinusoidal obstruction syndrome (HSOS) is a hepatic vascular disease histologically characterized by edema, necrosis, detachment of endothelial cells in small sinusoidal hepatic and interlobular veins and intrahepatic congestion, which leads to portal hypertension and liver dysfunction. In the Western world, most HSOS cases are associated w...
Oliveira, Ana Paula Pereira de Ferreira, Alexandre Rodrigues Fagundes, Eleonora Druve Tavares Queiroz, Thaís Costa Nascentes Carvalho, Simone Diniz Franco Neto, José Andrade Bittencourt, Paulo Fernando Souto
Abstract Objectives: This study aimed to evaluate factors associated with upper digestive hemorrhage and primary and secondary endoscopic prophylaxis outcomes in children with extrahepatic portal vein obstruction. Methods: This observational and prospective study included 72 children with extrahepatic portal vein obstruction who were followed from ...
Fukuda, Koshiro Sasaki, Takashi Hirasawa, Toshiaki Matsueda, Kiyoshi Nakao, Eisuke Mie, Takafumi Furukawa, Takaaki Yamada, Yuto Takeda, Tsuyoshi Kasuga, Akiyoshi
...
Published in
Clinical journal of gastroenterology
Duodenal varices are ectopic varices that are rare but can involve any site along the digestive tract outside the gastroesophageal region. Ectopic variceal bleeding is generally massive and life threatening; the mortality rate is approximately 40%. Up to 17% of ectopic varices occur in the duodenum. However, duodenal varices pose a significant ther...
Tejedor-Tejada, Javier Fuentes-Valenzuela, Esteban García-Pajares, Félix Nájera-Muñoz, Rodrigo Almohalla-Álvarez, Carolina Sánchez-Martín, Fátima Calero-Aguilar, Hermógenes Villacastín-Ruiz, Elena Pintado-Garrido, Rebeca Sánchez-Antolín, Gloria
...
Published in
Gastroenterologia y hepatologia
Transjugular intrahepatic portosystemic shunts (TIPS) are successfully used in the management of portal hypertension (PH)-related complications. Debate surrounds the diameter of the dilation. The aim was to analyse the outcomes of and complications deriving from TIPS in patients with cirrhosis and identify predictors of survival. This was a retrosp...
Zhang, Hui Zhang, Shaoying Zhang, Jian Zhou, Rui Nie, Yongzhan Ren, Song Li, Jun Feng, Keping Ji, Fanpu Kong, Guangyao
...
Published in
Platelets
Thrombocytopenia is a common hematological abnormality in patients with cirrhotic hypersplenism. Splenectomy with paraesophagogastric devascularization (SPD) is a conventional surgical therapy which can reverse pancytopenia in these patients. Platelets are traditionally recognized for their central role in hemostasis. However, the status of platele...
Desai, Archita P Knapp, Shannon M Orman, Eric S Ghabril, Marwan S Nephew, Lauren D Anderson, Melissa Ginès, Pere Chalasani, Naga P Patidar, Kavish R
Published in
Journal of hepatology
Acute kidney injury (AKI) is a significant clinical event in cirrhosis yet contemporary population-based studies on the impact of AKI on hospitalized cirrhotics are lacking. We aimed to characterize longitudinal trends in incidence, healthcare burden and outcomes of hospitalized cirrhotics with and without AKI using a nationally representative data...
Bai, Dou-Sheng Zhou, Bao-Huan Qian, Jian-Jun Zhang, Chi Jin, Sheng-Jie Jiang, Guo-Qing
Published in
Surgical endoscopy
Laparoscopic splenectomy and azygoportal disconnection (LSD) is widely used for the treatment of esophagogastric variceal haemorrhage and hypersplenism owing to cirrhotic portal hypertension. However, whether LSD improves liver synthesis function and cirrhosis remains unclear. The aim of this study is to investigate the effect of LSD on liver synth...
Chiang, Ryan S Parish, Alice Niedzwiecki, Donna Kappus, Matthew R Muir, Andrew J
Published in
Digestive diseases and sciences
Malnutrition is common in patients with cirrhosis and is associated with poor outcomes after hepatic resection and liver transplantation. Transjugular intrahepatic portosystemic shunt (TIPS) is performed for complications of cirrhosis. To assess the impact of malnutrition on TIPS outcomes. A retrospective analysis was performed using the Healthcare...
Guedes, Renata R Kieling, Carlos O Dos Santos, Jorge L da Rocha, Carolina Schwengber, Fernando Adami, Marina R Chedid, Marcio F Vieira, Sandra M G
Published in
Digestive diseases and sciences
Very few prior studies have investigated the presence of ascites as a prognostic factor in children with cirrhosis. To the best of our knowledge, there are no prior studies evaluating the relationship between severity of ascites and patient survival in children with biliary atresia and cirrhosis. To evaluate the association between severity of asci...