Current Research in Food Science
• The amount of loaded PMFs was improved by HIPE containing 80% MCT oil stabilized by WPI-LMP nanocomplexes. • The HIPE improved the digestion of oil phase compared to MCT oil according to the in vitro lipolysis study. • The HIPE improved the bioaccessibility of two major PMFs as evaluated by TIM-1 gastrointestinal model.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Polymethoxyflavones (PMFs) are widely found in Citri Reticulatae Pericarpium (CRP) and have been investigated with a broad spectrum of biological activities as well as health promoting properties. However, separation of the PMFs from a complex sample, especially preparative separation of these PMFs with high purity, remains challenging. In the pres...
Current Pharmacology Reports
Polymethoxyflavones (PMFs) are one group of the flavonoid compounds, with tangeretin (Tan) and nobiletin (Nob) being the most abundant PMFs in citrus peel. Numerous biological activities of PMFs have been intensively studied, including anti-inflammatory and anticancer activities. Because of their methoxy groups, PMFs are more lipophilic than hydrox...
JPC – Journal of Planar Chromatography – Modern TLC
Dikamali (Gardenia lucida Roxb., Rubiaceae family) is found to possess various ethno-medical properties, viz., anti-inflammatory, anthelmintic, cleaning foul ulcers, and wounds, to keep away flies from wounds in animals. In spite of having various medicinal properties, no validated analytical method has been reported so far for the quality assessme...
Dikamali gum (Gardenia lucida Roxb., Family—Rubiaceae) in wet and dry form is used as one of the popular tablet binders in the Indian traditional herbal formulations. Recently, its application as a binder in modern drug delivery has also been reported. However, its quality specification is yet to be established. To the best of our knowledge, no val...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
In the present study we mined the information on Gardenia lucida (Dikamali) and identified seven polymethoxyflavones from its gum resin. We also investigated its antiproliferative and antioxidant potential. Xanthomicrol (8) found as potent DPPH scavenger (85.86±1.3%) along with strong ferric plummeting ability (53.60±2.0 FSE) and reducing potential...
Journal of separation science
Polymethoxyflavones possess many biological properties, as lipid-lowering, hypoglycaemic, anti-inflammatory, antioxidant, and anticancer activities, therefore, they may be employed as nutraceuticals or therapeutic agents. The scarcity of pure polymethoxyflavones on the market as well as their low water solubility limited in vivo studies and the use...
Lantana ukambensis (Vatke) Verdc. is an African food and medicinal plant. Its red fruits are eaten and highly appreciated by the rural population. This plant was extensively used in African folk medicinal traditions to treat chronic wounds but also as anti-leishmanial or cytotoxic remedies, especially in Burkina Faso, Tanzania, Kenya, or Ethiopia. ...
Food Research International
•Food grade oil-in-water emulsions with different droplet sizes were manufactured.•The effects of emulsions on cellular update of 5-demethyltangeretin were determined.•The emulsion with smaller droplet size led to higher cellular uptake.•The emulsion with smaller droplet size led to stronger inhibition on cancer cells.
Journal of Functional Foods
The peel of citrus fruit is a valuable source of flavonoids and is used in folk medicine for the curing various diseases in East Asia. In this study, 11 flavonoids and one coumarin derivative in the peel of Citrus tangerina Hort. ex Tanaka (Pyunkyul), native to Korea, were characterized using high performance liquid chromatography–tandem mass spect...