In situ straining experiments were performed in a TEM on an equimolar CoCrFeMnNi (Cantor) high entropy alloy at room and cryogenic temperature. Perfect and partial dislocation activity were recorded in both cases. Twinning directly follows the development of partial dislocation shearing that has various origins (perfect dislocation splitting, ancho...
In this paper, glass fiber-reinforced polypropylene (GF50-PP) composite composed of long fibers was prepared by the thermo-compression process for the very first time. This composite presents high mechanical strength and is used in infrastructures, which demand resistance against severe conditions. Mechanical strength and multi-scale damage analysi...
We present in this investigation an advanced phenomenological approach combining the computational efficiency of classical phenomenological plasticity models and the accuracy and high resolution of multiscale crystal plasticity schemes. Within this advanced approach, a new phenomenological constitutive framework has been developed and implemented i...
Published in Neurosurgery
Gliomas exist within the framework of complex neuronal circuitry in which network dynamics influence both tumor biology and cognition. The generalized impairment of cognition or loss of language function is a common occurrence for glioma patients. The interface between intrinsic brain tumors such as gliomas and functional cognitive networks are poo...
Published in Acta Neuropathologica Communications
In this review, we discuss the synaptic aspects of Tau pathology occurring during Alzheimer’s disease (AD) and how this may relate to memory impairment, a major hallmark of AD. Whilst the clinical diagnosis of AD patients is a loss of working memory and long-term declarative memory, the histological diagnosis is the presence of neurofibrillary tang...
Published in NeuroImage : Clinical
Vision loss early in life has dramatic consequences on the organization of the visual system and hence on structural plasticity of its remnant components. Most of the studies on the anatomical changes in the brain following visual deprivation have focused on the re-organization of the visual cortex and its afferent and efferent projections. In this...
Published in International Journal of Pharmaceutics: X
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Funder: infinitus china ltd. / Abstract: In this review, we discuss the synaptic aspects of Tau pathology occurring during Alzheimer’s disease (AD) and how this may relate to memory impairment, a major hallmark of AD. Whilst the clinical diagnosis of AD patients is a loss of working memory and long-term declarative memory, the histological diagnosi...
Published in BMC Genomics
BackgroundLoss of pancreatic insulin-secreting β-cells due to metabolic or autoimmune damage leads to the development of diabetes. The discovery that α-cells can be efficiently reprogrammed into insulin-secreting cells in mice and humans has opened promising avenues for innovative diabetes therapies. β-cell loss triggers spontaneous reprogramming o...
Published in Brain imaging and behavior
The aim of this study is to examine cortical plasticity and to analyze cortical reorganization following hand and facial transplantation, using functional magnetic resonance imaging. Patients who had undergone full-face transplantation, hand transplantation and scapular arm replantation, as well as healthy controls, participated in the study. The p...
