Plan de gestion de données de la structure Plateforme Tropicale d'Expérimentation sur l'Animal
Adaptive immune response to a wild boar-derived recombinant hepatitis e virus capsid protein challenge in pigs.
Published in Vaccine
Hepatitis E virus genotype 3 (HEV-3) is a zoonotic pathogen capable of infecting human, porcine, and other animal hosts. Despite a broad host range and abundance of species that act as reservoirs for human infections, no commercially available animal vaccines against HEV-3 are currently available. In the present study, we tested the capacity of rec...
A New Experimental Animal Model of Pararenal Aortic Aneurysm Suitable for Fenestrated Endovascular Aneurysm Repair.
CREBRF regulates apoptosis and estradiol via ISG15/ISGylation in pig granulosa cells.
Published in Free radical biology & medicine
Granulosa cells play a crucial role in the reproductive processes of female animals, as their proliferation, apoptosis, and hormonal secretion are vital for follicular development and ovulation. Although the role and mechanisms of CREBRF in the reproductive system have been partly reported, its functions in ovarian granulosa cells have not been ful...
"Thirteen ways of looking at a dead pig" / "Thirteen ways of looking at a dead pig": About Damien Hirst's This Little Pi...
If De Quincey evoked “murder as one of the fine arts”, fine arts have always been the locus of animal murders, but that is slowly emerging as a topic of research. Former Young British Artist Damien Hirst is notorious for having caused the deaths of more than one million insects and animals – over a period when the world was putting to death million...
A variety of cytochrome P450 enzymes and flavin-containing monooxygenases in dogs and pigs commonly used as preclinical ...
Published in Biochemical pharmacology
Drug oxygenation is mainly mediated by cytochromes P450 (P450s, CYPs) and flavin-containing monooxygenases (FMOs). Polymorphic variants of P450s and FMOs are known to influence drug metabolism. Species differences exist in terms of drug metabolism and can be important when determining the contributions of individual enzymes. The success of research...
Melatonin protects against defects induced by methoxychlor in porcine oocyte maturation.
Published in Cell cycle (Georgetown, Tex.)
Methoxychlor (MXC) is a widely used organochlorine pesticide primarily targeting pests. However, MXC has been found to negatively impact the reproductive system of both humans and animals, triggering oxidative stress and apoptosis. Melatonin (MLT), an endogenous hormone, possesses various benefits, including circadian rhythm regulation and anti-inf...
Immune transcriptomic profile in adult female pigs: dominance status has more influence than environmental enrichment
Background - Assessing farm animals’ welfare is crucial, yet practical physiological tools are still lacking. In this study, we tested whether the peripheral blood mononuclear cell (PBMC) transcriptome shows variations in association with sows’ welfare. To do this, we compared animals whose welfare states were assumed to differ due to their lives i...
First study in the frequency of isolation and phenotypic antimicrobial resistance profiles of pig and cattle origin Camp...
...Published in Veterinary research communications
Campylobacter spp. is recognized as one of the most common pathogens involved in the development of gastrointestinal infections in humans. The current study aimed to enhance the knowledge on the occurrence and molecular characterization of Campylobacter spp. in pigs and cattle origin caecum samples (n = 56) collected in one year, from nine Romanian...
Structure-dependent degradation of milk oligosaccharides by newly isolated intestinal commensal bacterial strains from s...
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Objective:Milk oligosaccharides (MOs), first prebiotics for neonates, regulate intestinal microbial composition and may influence long-term health. However, the high structural diversity of MOs among mammalian species, which influences the holobiont development, remains to be explored. This study analyses in vitro functional links between MO struct...
