Published in npj Microgravity
Modifications of gravity levels induce generalized adaptation of mammalian physiology, including vascular, brain, muscle, bone and immunity functions. As a crucial interface between the vascular system and the brain, the blood–brain barrier (BBB) acts as a filter to protect neurons from pathogens and inflammation. Here we compare the effects of sev...
Tobacco cigarette (TC) smoking has never been lower in the United States, but electronic cigarette (EC) vaping has reached epidemic proportions among our youth. Endothelial dysfunction, as measured by flow-mediated vasodilation (FMD) is a predictor of future atherosclerosis and adverse cardiovascular events and is impaired in young TC smokers, but ...
Published in BMC Veterinary Research
BackgroundCastration is a husbandry practice raising important questions on the welfare and physiological status of farm animals. Searching for effective castration methods that minimally compromise the body physiology is worthy of attention. Therefore, this study aimed to evaluate the differential response of biological systems in donkeys to surgi...
Published in Frontiers in Zoology
BackgroundInvasive species are of substantial concern because they may threaten ecosystem stability and biodiversity worldwide. Not surprisingly, studies examining the drivers of biological invasion have increased in number over the past few decades in an effort to curtail invasive species success by way of informing management decisions. The commo...
Published in BMC Medical Education
BackgroundIn medical physiology, educators and students face a serious challenge termed misconceptions. Misconceptions are incorrect ideas that do not match current scientific views. Accordingly, they have shown to hamper teaching and learning of physiological concepts. Conceptual Change Theory forms the basis of new teaching and learning practices...
Published in Journal of medical biography
Professor Juan Negrín López was Prime Minister of the democratically elected left-wing government of Spain for the latter two-and-a-half years of the three-year Civil War which ravaged the country between 1936 and 1939. The side loyal to the government lost, partly because of the generous aid received by their opponents from Germany and Italy, part...
Published in Journal of pharmacokinetics and pharmacodynamics
The extensive metabolic demands of pregnancy require specific physiological and anatomical changes. These changes affect almost all organ systems, including the cardiovascular, respiratory, renal, gastrointestinal, and hematologic system. The placenta adds another layer of complexity. These changes make it challenging for clinicians to understand p...
Published in Quarterly journal of experimental psychology (2006)
Spatial-numerical and spatial-positional associations have been well documented in the domains of numerical cognition and working memory, respectively. However, such associations are typically calculated by directly comparing (e.g., subtracting) left- versus right-hand responses; it remains an open question whether such associations reside in each ...
The gut microbiome has the potential to create or modify xenometabolites (i.e., nonhost-derived metabolites) through de novo synthesis or modification of exogenous and endogenous compounds. While there are isolated examples of xenometabolites influencing host health and disease, wide-scale characterization of these metabolites remains limited. We d...
Published in Journal of science and medicine in sport
To compare fixed epochs (FIXED) and rolling averages (ROLL) for quantifying worst-case scenario ('peak') running demands during professional soccer match-play, whilst assessing contextual influences. Descriptive, observational. Twenty-five outfield players from an English Championship soccer club wore 10-Hz microelectromechanical systems during 28 ...
