Odorants have a major importance for the evaluation of food. Thousands of odorants occur in foodstuffs, but only a small minority of them plays a role for the conscious perception of food aromas. Some odorants can be quite similar on the basis of their chemical properties but strikingly different in their sensory properties, yet others surprise wit...
Published in Wiener Medizinische Wochenschrift
Pharmacological research confirms and supports the clinically observed antidepressant efficacy of St. John’s wort (Hypericum perforatum L., SJW). This contribution is an update of a former review by the authors in 2007. Positive evidence of antidepressant effects has been found with SJW preparations, extract fractions, and single constituents. The ...
Published in Wiener Medizinische Wochenschrift
Silexan is an essential oil produced from Lavandula angustifolia flowers with proven clinical efficacy for the treatment of anxiety disorders. The present study was conducted to assess its anxiolytic activity and to screen for neuropharmacological properties in rats and mice of either sex. Silexan (3, 10, and 30 mg/kg, intraperitoneally), lorazepam...
Published in Herz Kardiovaskuläre Erkrankungen
Principally, there are two reasons why the pharmacological response to antiplatelet drugs should be measured: on the one hand, an insufficient inhibition of platelet function may result in atherothrombotic complications; on the other hand, an excessive inhibition of platelet function may lead to bleeding complications. The clinical importance to me...
Published in Wiener Medizinische Wochenschrift
St. John's wort (Hypericum perforatum L., SJW) contains numerous compounds with documented biological activity. Constituents that have stimulated the most interest include the naphthodianthrones hypericin and pseudohypericin, a broad range of flavonoids, and the phloroglucinols hyperforin and adhyperforin. According to the actual state of scientifi...
Published in European Surgery
BACKGROUND: A multimodal approach to perioperative pain, including nonsteroidal anti-inflammatory drugs (NSAIDs) is recommended. Lornoxicam is an NSAID of the oxicam class. METHODS: Review on Lornoxicam. RESULTS: Lornoxicam is available in oral (standard and quick-release) and parenteral formulations. It is characterised by a relatively quick onset...
Published in Schweizerische Zeitschrift für Ganzheitsmedizin / Swiss Journal of Integrative Medicine
Es wird ein Überblick Über die Botanik, Drogengewinnung, Inhaltsstoffe, Pharmakologie und Klinik des Hopfens bzw. der Hopfenzapfen gegeben. WÄhrend fÜr die sedierende Wirkung bisher keine Inhaltsstoffe als verantwortlich genannt werden kÖnnen, sind in letzter Zeit fÜr einige Flavonoide interessante pharmakologische Effekte entdeckt worden. Die Anwe...
Tissue Engineering gilt als vielversprechendes Verfahren zur Herstellung einfach organisierter Gewebe außerhalb des Körpers, die als in-vitro-Testsysteme im Bereich der Medikamentenentwicklung und der Medizintechnik eingesetzt werden. Die Herstellung komplexer Organsysteme wie Leber, Niere oder Herz ist bislang noch nicht realisierbar. Ein großers ...
