Antimalarial Activity of Novel Substituted N-Arylcinnamamides
Comparison of several strategies for the deployment of a multivariate regression model on several handheld NIR instrumen...
Chemometrics applied to spectroscopic measurements such as near-infrared are gaining more and more importance for quality control of pharmaceutical products. Handheld near-infrared devices show great promise as a medicines quality screening technique for post-marketing surveillance. These devices are able to detect substandard and falsified medicin...
Analytical performance of eight enzymatic assays for ethanol in serum evaluated by data from the Belgian external qualit...
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Abstract
DD-SIMCA and PLS regression models applied to NIR spectroscopy for identification and assay of ciprofloxacin tablets
peer reviewed / Poor-quality medicines pose a threat to the health of populations but also constitute a hindrance to the socio-economic development of governments. Developing countries are the most affected, as they face enormous difficulties in ensuring the quality of medicines present in their markets [1]. Among other difficulties, the methods co...
PHARMACOLOGICAL ASSESSMENT OF CONSTITUENTS OF SPECIES ALLIUM SAXATILE AND ALLIUM PONTICUM GROWING IN GEORGIA
editorial reviewed / The present study aimed to estimate the pharmacological potency of products from some Allium species - Allium saxatile and Allium ponticum, growing in Georgia. Analgesic, anti-inflammatory and gastroprotective activity of total extracts and fractions were evaluated using accepted in vivo models: hot-plate, carrageenan-induced e...
A pharmaceutical-related molecules dataset for reversed-phase chromatography retention time prediction built on combinin...
There is a rising interest in the modeling and predicting of chromatographic retention. The progress towards more complex and comprehensive models emphasized the need for broad reliable datasets. The present dataset comprises small pharmaceutical compounds selected to cover a wide range in terms of physicochemical properties that are known to impac...
Cannabidiol: a deserved popularity ? Interest of toxicological analysis
peer reviewed
Super-conserved receptors expressed in the brain: biology and medicinal chemistry efforts.
The super-conserved receptors expressed in the brain (SREB) constitute a family of orphan G protein-coupled receptors that include GPR27 (SREB1), GPR85 (SREB2) and GPR173 (SREB3). Their sequences are highly conserved in vertebrates, and they are almost exclusively expressed in the central nervous system. This family of receptors has attracted much ...
When therapeutic drugs lead to diabetes.
Drug-induced diabetes mellitus is a growing problem in clinical practice. New, potent medications contribute to this problem in a population already at high risk of developing glucose disturbances because of poor lifestyle habits and high prevalence of being overweight/obese. The present review focuses on four important pharmacological classes: glu...
Superconserved receptors expressed in the brain: Expression, function, motifs and evolution of an orphan receptor family...
peer reviewed
