Ji, Li-Qin Rao, Ying-Zhu Zhang, Yong Chen, Rong Tao, Ya-Xiong
Published in
General and comparative endocrinology
Melanocortin-1 receptor (MC1R) has important roles in regulating pigmentation and inflammation. Melanocortin receptor accessory protein 2 (MRAP2) modulates trafficking, ligand binding, and signaling of mammalian melanocortin receptors. However, the effect of MRAP2 on fish MC1R has not been extensively studied. Herein, we cloned the orange-spotted g...
Keates, Simeon
Published in
Universal Access in the Information Society
Designing for Universal Access requires designers to have a good understanding of the full range of users and their capabilities, appropriate datasets, and the most suitable tools and techniques. Education clearly plays an important role in helping designers acquire the knowledge and skills necessary to find the relevant information about the users...
Jödicke, Annika M. Zellweger, Urs Tomka, Ivan T. Neuer, Thomas Curkovic, Ivanka Roos, Malgorzata Kullak-Ublick, Gerd A. Sargsyan, Hayk Egbring, Marco
Published in
BMC Health Services Research
BackgroundRising health care costs are a major public health issue. Thus, accurately predicting future costs and understanding which factors contribute to increases in health care expenditures are important. The objective of this project was to predict patients healthcare costs development in the subsequent year and to identify factors contributing...
Tapley, Patrick Kellett, Suzanne
Published in
Perioperative Medicine
The increasing availability of cannabis for both recreational and medicinal purposes means that anaesthetists will encounter an increasing number of patients taking cannabis-based medications. The existing evidence base is conflicted and incomplete regarding the indications, interactions and long-term effects of these substances. Globally, most doc...
Rammohan, Aluru Reddy, Guda Mallikarjuna Bhaskar, Baki Vijaya Gunasekar, Duvvuru Zyryanov, Grigory V.
Published in
Planta
Main conclusionThe genus Rhynchosia is a rich source of natural compounds especially flavonoids and prenylated isoflavonoids. Further experimental studies on Rhynchosia members may be result new and novel secondary metabolites with potent biological activities.AbstractTraditionally, medicinal plants have played a significant role on human life sinc...
Kühbeck, Felizian Berberat, Pascal O. Engelhardt, Stefan Sarikas, Antonio
Published in
BMC Medical Education
BackgroundLearning analytics aims to improve learning outcomes through the systematic measurement and analysis of learning-related data. However, which parameters have the highest predictive power for academic performance remains to be elucidated. The aim of this study was to investigate the correlation of different online assessment parameters wit...
Schwiebs, Anja Wang, Yong Moore, Andrew M Zhu, Xudong Pankow, Kristin Siems, Wolf-Eberhard Walther, Thomas
Published in
British journal of pharmacology
The B-type natriuretic peptide (BNP1-32) exerts vasorelaxing and cardioprotective activity. BNP is used as a biomarker for the diagnosis of cardiopathological conditions and recombinant BNP1-32 as a drug for the treatment of such. BNP1-32 has a short half-life time and thus, similar to other vasoactive peptides like angiotensin II and bradykinin, c...
Oberheim Bush, Nancy Ann Hervey-Jumper, Shawn L Berger, Mitchel S
Published in
World neurosurgery
Glioblastomas are the most common malignant brain tumor and despite extensive research have a dismal prognosis. This review focuses on the current treatment paradigms of glioblastoma and highlights current advances in surgical approaches, imaging techniques, molecular diagnostics, and translational efforts. Several promising clinical trials in immu...
Orso, Daniele Boaro, Genny Cassan, Emanuela Guglielmo, Nicola
Published in
European journal of internal medicine
Barletta, Michele Reed, Rachel
Published in
The Veterinary clinics of North America. Small animal practice
Local anesthetics are the only class of drugs that can block transduction and transmission of nociception. Physical properties, mechanism of action, and pharmacokinetics of this class of drugs are reviewed in this article. The clinical use, such intravenous administration of lidocaine, and local and systemic toxic effects are covered. A review of c...
