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Baliga, Pallavi Goolappa, Puneeth Thadooru Shekar, Malathi Kallappa, Girisha Shivani
Published in
Probiotics and antimicrobial proteins
Multidrug-resistant bacteria are emerging as a major global threat to public health. Bacteriophages are an important source of antimicrobial enzymes and could be developed as an alternative antibiotic candidate. This study investigates the antibacterial capacity of the endolysin LysE against Aeromonas hydrophila. The endolysin LysE gene was cloned ...
Lu, Shao-Yeh Bischoff, Kenneth M. Rich, Joseph O. Liu, Siqing Skory, Christopher D.
Published in
Biotechnology for Biofuels
BackgroundCommercial ethanol fermentation facilities traditionally rely on antibiotics for bacterial contamination control. Here we demonstrate an alternative approach to treat contamination using a novel peptidoglycan hydrolase (LysKB317) isolated from a bacteriophage, EcoSau. This endolysin was specially selected against Lactobacillus strains tha...
Kim, Shukho Lee, Da-Won Jin, Jong-Sook Kim, Jungmin
Published in
Journal of global antimicrobial resistance
Multidrug-resistant (MDR) bacteria are a major public-health concern. Bacteriophage endolysins (lysins) can be used as novel antimicrobial agents against bacterial infections. In this study, a novel endolysin (LysSS) containing a lysozyme-like domain was evaluated for its antibacterial activity against various species of bacteria. The LysSS-encodin...
Ciepluch, Karol Maciejewska, Barbara Gałczyńska, Katarzyna Kuc-Ciepluch, Dorota Bryszewska, Maria Appelhans, Dietmar Drulis-Kawa, Zuzanna Arabski, Michał
Published in
Bioorganic chemistry
Nowadays, the researchers make a big effort to find new alternatives to overcome bacterial drug resistance. One option is the application of bacteriophage endolysins enable to degrade peptidoglycan (PG) what in consequence leads to bacterial cell lysis. In this study we examine phage KP27 endolysin mixed with poly(propyleneimine) dendrimers to eval...
