Park, Young-Kyoung Sellés Vidal, Lara Bell, David Zabret, Jure Soldat, Mladen Kavšček, Martin Ledesma-Amaro, Rodrigo
Abstract Background Limonene has a variety of applications in the foods, cosmetics, pharmaceuticals, biomaterials, and biofuels industries. In order to meet the growing demand for sustainable production of limonene at industry scale, it is essential to find an alternative production system to traditional plant extraction. A promising and eco-friend...
Liu, Meng He, Li
Published in
Cellular and molecular life sciences : CMLS
The high-protein diet (HPD) has emerged as a potent dietary approach to curb obesity. Peroxisome, a highly malleable organelle, adapts to nutritional changes to maintain homeostasis by remodeling its structure, composition, and quantity. However, the impact of HPD on peroxisomes and the underlying mechanism remains elusive. Using Drosophila melanog...
中西, 浩平
京都大学 / 新制・課程博士 / 博士(農学) / 甲第25337号 / 農博第2603号 / 新制||農||1106(附属図書館) / 京都大学大学院農学研究科応用生命科学専攻 / (主査)教授 矢﨑 一史, 教授 山口 信次郎, 教授 飛松 裕基 / 学位規則第4条第1項該当 / Doctor of Agricultural Science / Kyoto University / DGAM
Manandhar, Laxman Dutta, Raghbendra Kumar Devkota, Pradeep Chhetri, Arun Wei, Xiaofan Park, Channy Kwon, Hyug Moo Park, Raekil
Published in
Cell communication and signaling : CCS
Calcium is a ubiquitous intracellular messenger that regulates the expression of various genes involved in cell proliferation, differentiation, and motility. The involvement of calcium in diverse metabolic pathways has been suggested. However, the effect of calcium in peroxisomes, which are involved in fatty acid oxidation and scavenges the result ...
Ghzaiel, Imen Maaloul, Samah Ksila, Mohamed Namsi, Amira Yammine, Aline Debbabi, Meriam Badreddine, Asma Meddeb, Wiem Pires, Vivien Nury, Thomas
...
7-Ketocholesterol and 7β-hydroxycholesterol are most often derived from the autoxidation of cholesterol. Their quantities are often increased in the body fluids and/or diseased organs of patients with age-related diseases such as cardiovascular diseases, Alzheimer’s disease, age-related macular degeneration, and sarcopenia which are frequently asso...
Martin de Fourchambault, Esther
L'hépatite C est une maladie chronique occasionnant une atteinte hépatique évolutive pouvant conduire en 20 ou 30 ans à l'apparition d'une cirrhose ou d'un hépatocarcinome. L'agent pathogène responsable de cette maladie est le virus de l'hépatite C (HCV). C'est un petit virus enveloppé à ARN monocaténaire de polarité positive qui infecte les hépato...
Guo, Yanyan Zhou, Pei Qiao, Lei Guan, Hongbo Gou, Jian Liu, Xiaomei
Published in
The Journal of nutritional biochemistry
Maternal protein malnutrition leads to liver dysfunction and increases susceptibility to nonalcoholic fatty liver disease in adult fetal growth restriction (FGR) offspring, yet the underlying mechanism remains unknown. Peroxisomes play vital roles in fatty acid β-oxidation (FAO) and detoxification of reactive oxygen species (ROS). Using a well-defi...
Tawbeh, Ali
Microglia act as the immune sentinel of the central nervous system and play a crucial role in maintaining its homeostasis. Peroxisomes, essential organelles in cellular metabolism, mainly orchestrate the breakdown of very long-chain fatty acids (VLCFAs). The accumulation of VLCFAs is a marker of peroxisomal diseases, the most common of which is X-l...
Figueiredo Costa, Cláudio; 131598; Lismont, Celien; 92641; Anteghini, Marco; Revenco, Iulia; Li, Hongli; Fransen, Marc; 2737;
As befits their name, peroxisomes play a central role in cellular hydrogen peroxide (H₂O₂) metabolism. In addition, it is increasingly appreciated that changes in peroxisomal H₂O₂ metabolism can actively contribute to the initiation and progression of redox stress-related human pathologies such as cancer, diabetes, and neurodegeneration. However, t...
Ali, Bashir A Judy, Ryan M Chowdhury, Saikat Jacobsen, Nicole K Castanzo, Dominic T Carr, Kaili L Richardson, Chris D Lander, Gabriel C Martin, Andreas Gardner, Brooke M
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Published in
bioRxiv : the preprint server for biology
The heterohexameric AAA-ATPase Pex1/Pex6 is essential for the formation and maintenance of peroxisomes. Pex1/Pex6, similar to other AAA-ATPases, uses the energy from ATP hydrolysis to mechanically thread substrate proteins through its central pore, thereby unfolding them. In related AAA-ATPase motors, substrates are recruited through binding to the...
