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Maeng, Joon-Ho Jeong, Hyo Eun Shin, Hyun-Joon Kim, Sehoon Lee, Jong-Chul Lee, Jaeyoung Chung, Seok Lee, Sangyoup
Published in
Microfluidics and Nanofluidics
Proliferation characteristics of CHO-K1 cells were investigated under a variety of medium perfusion rate conditions in a microfluidic perfusion cell culture platform. Five microcavities of 800μm(w)×800μm(l)×400μm(h)\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} ...
Huang, Huang-Wen Shih, Tzu-Ching Liauh, Chihng-Tsung
Published in
BioMedical Engineering OnLine
BackgroundPennes Bio Heat Transfer Equation (PBHTE) has been widely used to approximate the overall temperature distribution in tissue using a perfusion parameter term in the equation during hyperthermia treatment. In the similar modeling, effective thermal conductivity (Keff) model uses thermal conductivity as a parameter to predict temperatures. ...
Levitt, David G
Published in
BMC Clinical Pharmacology
BackgroundThe goal of physiologically based pharmacokinetics (PBPK) is to predict drug kinetics from an understanding of the organ/blood exchange. The standard approach is to assume that the organ is "flow limited" which means that the venous blood leaving the organ equilibrates with the well-stirred tissue compartment. Although this assumption is ...
Viterbo, Fausto Siclovan, Horia
Published in
Aesthetic Plastic Surgery
Korolevich, A. N. Astaf’eva, L. G. Dubina, N. S. Vecherinskii, S. I. Belsley, M. S.
Published in
Optics and Spectroscopy
The rate of microcirculation of blood in human skin is studied in vivo in the normal state and in the presence of cardiovascular diseases. It is shown experimentally that low-intensity laser radiation affects the rheological characteristics of erythrocytes. To explain the results obtained, a model for calculating the heating of blood in capillaries...
Izumi, Yotaro Yamahata, Takeshi Yozu, Ryohei Kobayashi, Koichi Mukai, Makio
Published in
The Japanese Journal of Thoracic and Cardiovascular Surgery
The oxygen transporting capability of an artificial oxygen carrier NRC was evaluated by employing it as a perfusate for total cardiopulmonary bypass. NRC is a type of liposome encapsulated hemoglobin. It has a particle size of approximately 220 nm, with a hemoglobin concentration of 5.6 g/dl and its P50 is controlled to 45 Torr. Male beagles were u...
Il’yasov, K. A. Eissner, B. Hennig, J.
Published in
Applied Magnetic Resonance
The effect of perfusion on the temperature distribution during radio-frequency hyperthermia and laser-induced thermotherapy was investigated with the perfused porcine kidney model. The phase shift-based proton resonance frequency shift method was used to map the temperature distribution. In experiments with modulated perfusion rates it was demonstr...
