Larsson, Sara Marie Hillarp, Andreas Karlsland Åkeson, Pia Hellström-Westas, Lena Domellöf, Magnus Askelöf, Ulrica Götherström, Cecilia Andersson, Ola
Published in
International journal of laboratory hematology
Infant iron status assessments may be difficult to interpret due to infections. The soluble transferrin receptor (sTfR) has been suggested as a biomarker mainly unaffected by the acute phase response. Reference intervals reflecting dynamics of infant growth first year in life are not well established. The sTfR and CRP concentrations were measured i...
Alhasan, Khalid Abdulaziz Al Khalifah, Reem Aloufi, Majed Almaiman, Weiam Hamad, Muddathir Abdulmajeed, Naif Al Salloum, Abdullah Kari, Jameela A AlJelaify, Muneera Bassrawi, Rolan K
...
Published in
Systematic reviews
Nephrotic syndrome is the most common kidney disease in children worldwide. Our aim was to critically appraise the quality of recent Clinical Practice Guidelines (CPGs) for idiopathic steroid-sensitive nephrotic syndrome (SSNS) in children in addition to summarize and compare their recommendations. Systematic review of CPGs. We identified clinical ...
Humoodi, Mohamed O. Aldabbagh, Mona A. Salem, Maher M. Al Talhi, Yousef M. Osman, Sara M. Bakhsh, Mohammed Alzahrani, Abdullah M. Azzam, Maha
Published in
BMC Pediatrics
BackgroundPediatric sepsis remains a significant cause of morbidity and mortality worldwide. This study aimed to identify the incidence of sepsis and septic shock among patients admitted to the pediatric intensive care unit (PICU) of a tertiary center in Saudi Arabia. Patients' demographics and risk factors associated with sepsis-related mortality ...
Cristea, Sînziana Krekels, Elke H. J. Allegaert, Karel De Paepe, Peter de Jaeger, Annick De Cock, Pieter Knibbe, Catherijne A. J.
Published in
The AAPS Journal
To date, information on the ontogeny of renal transporters is limited. Here, we propose to estimate the in vivo functional ontogeny of transporters using a combined population pharmacokinetic (popPK) and physiology-based pharmacokinetic (PBPK) modeling approach called popPBPK. Clavulanic acid and amoxicillin were used as probes for glomerular filtr...
Cristea, Sînziana; Krekels, Elke HJ; Allegaert, Karel; 46648; De Paepe, Peter; de Jaeger, Annick; De Cock, Pieter; Knibbe, Catherijne AJ;
To date, information on the ontogeny of renal transporters is limited. Here, we propose to estimate the in vivo functional ontogeny of transporters using a combined population pharmacokinetic (popPK) and physiology-based pharmacokinetic (PBPK) modeling approach called popPBPK. Clavulanic acid and amoxicillin were used as probes for glomerular filtr...
Kebede, Destaw Admas, Alemale Mekonnen, Daniel
Published in
BMC Microbiology
BackgroundStreptococcus pyogenes (S. pyogenes) is a Gram positive bacterium which is a leading cause of pharyngitis, skin and soft tissue infection and post streptococcal syndromes. Due to lack of β-lactamase enzyme production, it was considered universally susceptible to penicillin group and later generation of β-lactam antibiotics. As such, empir...
Marsh, Melanie Lauden, Stephanie M Mahan, John D Schneider, Lydia Saldivar, Laura Hill, Nina Diaz, Christopher Abdel-Rasoul, Mahmoud Reed, Suzanne
Published in
Patient education and counseling
There are few opportunities in medical education dedicated to learning skills for effective communication in life altering patient scenarios. We therefore aimed to develop and assess a longitudinal advanced communication curriculum for pediatric residents using patient feedback and deliberate practice. Pediatric residents at a large academic center...
Go, Kyeong-O Lee, Minji Lim, Yeji Lee, Kyu Sang Choe, Gheeyoung Kim, Chae-Yong
Published in
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery
Subependymoma is a slow-growing, exophytic, intraventricular glial neoplasm that commonly arises in the ventricular system. However, a report found that the frequency of intracerebral subependymoma was 0.4% in 1000 routine autopsies. To the best of our knowledge, only seven cases of intracerebral subependymoma have been reported. We report a rare c...
Hess, Clayton B Parkes, Jeannette Janssens, Geert O Lin, Chi Wong, Kenneth Zaghloul, Mohamed S Marconi, Daniel G Boterberg, Tom Esiashvili, Natia
Published in
Pediatric blood & cancer
This report provides a summary of the global burden of childhood cancer morbidity and mortality, which disproportionately affects low- and middle-income countries as well as low- and middle-income communities within high-income countries. We review past successes and current challenges to improving clinical pediatric radiotherapy, education, and re...
Fikse, Derek J Grenz, Phillip M Wheatley, Scott M Fugok, Kimberly L
Published in
The American journal of emergency medicine
Henoch Schonlein Purpura is a rare hypersensitivity vasculitis that is commonly associated with pediatric patients. It typically presents with purpuric rash to the lower extremities, abdominal pain and microscopic hematuria; however, it may also be associated with intussusception, glomerulonephritis and hypertension. Posterior Reversible Encephalop...
