Simpson, Jane Zarotti, Nicolò Varey, Sandra Anestis, Eleftherios Holland, Carol Murray, Craig Eccles, Fiona Jr
Published in
Chronic illness
The purpose of this study was to explore the experiences of individuals with Parkinson's through the theoretical lens of illness uncertainty during the first UK full lockdown period (March-June 2020) put in place due outbreak of the COVID-19 pandemic. Individual semi-structured interviews were carried out via telephone in May 2020 with 10 individua...
Gonçalves, Valeria C Cuenca-Bermejo, Lorena Fernandez-Villalba, Emiliano Martin-Balbuena, Sebastian da Silva Fernandes, Maria Jose Scorza, Carla A Herrero, Maria-Trinidad
Published in
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry
It has been more than 200 years since James Parkinson made the first descriptions of the disease that bears his name. Since then, knowledge about Parkinson's disease has been improved, and its pathophysiology, diagnosis, and treatments are well described in the scientific and medical literature. However, there is no way to prevent the disease from ...
Cocks, Naomi Rafols, Jonathan Embley, Elizabeth Hill, Kylie
Published in
Dysphagia
One of the most debilitating symptoms of advanced Parkinson's disease is drooling. Currently, the main treatment that is offered for drooling is botulinum toxin injections to the saliva glands which have a number of side effects and do not treat the causes of drooling, such as impaired swallowing and lip closure. This study explored the effect of a...
Behrman, Alison Cody, Jennifer Chitnis, Shilpa Elandary, Samantha
Published in
Logopedics, phoniatrics, vocology
SPEAK OUT! with The LOUD Crowd is a standardized speech therapy program typically consisting of 12 one-on-one treatments and ongoing weekly group maintenance sessions for patients with dysarthria due to Parkinson's disease (PD). It is based upon the hypothesis that increased attention to speech, which is a goal-directed motor activity, may compensa...
Guan, Xiao-Jun Guo, Tao Zhou, Cheng Gao, Ting Wu, Jing-Jing Han, Victor Cao, Steven Wei, Hong-Jiang Zhang, Yu-Yao Xuan, Min
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Brain radiomics can reflect the characteristics of brain pathophysiology. However, the value of T1-weighted images, quantitative susceptibility mapping, and R2* mapping in the diagnosis of Parkinson's disease (PD) was underestimated in previous studies. In this prospective study to establish a model for PD diagnosis based on brain imaging informati...
Bosch, Taylor J Groth, Christopher Singh, Arun
Published in
Cerebellum (London, England)
Recent anatomical studies have shown connections between the basal ganglia and the cerebellum. The basal ganglia and cerebellum are major subcortical structures that influence motor and cognitive functions. Recent neuroimaging and animal studies have suggested the role of the cerebellum in the pathophysiology of Parkinson's disease. However, the ro...
Long, Tao Tang, Yong He, Yan-Ni He, Chang-Long Chen, Xue Guo, Min-Song Wu, Jian-Ming Yu, Lu Yu, Chong-Lin Yuen-Kwan Law, Betty
...
Published in
The journals of gerontology. Series A, Biological sciences and medical sciences
Nutrition intervention has emerged as a potential strategy to delay aging and promote healthy longevity. Citri Reticulatae Semen (CRS) has diverse beneficial effects and has been used for thousands of years to treat pain. However, the health benefits of CRS in prolonging health span and improving aging-related diseases and the exact mechanisms rema...
Mantovani, Elisa Tamburin, Stefano
Published in
The international journal of neuropsychopharmacology
Chemosensory (i.e., olfaction and taste) dysfunction is common in neurodegenerative (e.g., Parkinson's disease, Alzheimer's disease, and dementia), psychiatric (e.g., depression, bipolar disorders, other conditions), and postinfectious (i.e., long COVID) diseases and in the elderly. Despite its impact on patients' quality of life, no established tr...
Siquier, Antònia Andrés, Pilar
Published in
Frontiers in Psychology
Objective Memory impairment is a hallmark cognitive deficit in Parkinson’s disease (PD). However, it remains unclear which processes underlie this deficit in PD. Also, little is known on these patients’ subjective experiences of memory difficulties and their relationship with objective measures. We aim to portray memory deficits in PD by combining ...
Xiao, Yi Wei, Qianqian Ou, Ruwei Hou, Yanbing Zhang, Lingyu Liu, Kuncheng Lin, Junyu Yang, Tianmi Jiang, Qirui Shang, Huifang
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Published in
Frontiers in Aging Neuroscience
Background The different clinical characteristics and prognostic values of the motor-nonmotor subtypes of Parkinson’s disease (PD) have been established by previous studies. However, the consistency of motor-nonmotor subtypes in patients with early-stage Parkinson’s disease required further investigation. The present study aimed to evaluate the con...
