Published in Scientific Reports
Malaria transmission after universal access and use of malaria preventive services is known as residual malaria transmission. The concurrent spatial-temporal distributions of people and biting mosquitoes in malaria endemic villages determines where and when residual malaria transmission occurs. Understanding human and vector population behaviors an...
Published in Heliyon
Microbiology; Biocomputational method; Leishmania; Enzyme kinetics; Chromatography; Biomolecules; Parasitology; Leishmania braziliensis; Nicotinate/nicotinamide mononucleotide adenylyltransferase (NMNAT); Nicotinamide adenine dinucleotide (NAD); Oligomeric states; Kinetic characterization.
Published in Malaria Journal
BackgroundDissolution of artemether (ART) and lumefantrine (LUM) active pharmaceutical ingredients (APIs) in fixed dose combination (FDC) ART/LUM tablets is one of the critical quality attributes. Thus, the verification of the release profile of ART and LUM from FDC ART/LUM tablets using a robust and discriminatory dissolution method is crucial. Th...
Published in Heliyon
Biotechnology; Epidemiology; Infectious Disease; Parasitology; Public Health; Plasmodium falciparum; dihydrofolate reductase (dhfr) gene; single nucleotide polymorphisms (SNPs); sequence analysis.
Published in Scientific Reports
The parasitic nematode Trichuris trichiura is a significant burden on public health in developing countries, and currently available drugs exhibit a poor cure rate. Worms live within a specialised tunnel of host intestinal epithelial cells and have anterior-ventral projections of the cuticle termed “cuticular inflations”, which are thought to be in...
Published in Scientific Data
Measurement(s) DistributionTechnology Type(s)digital curationFactor Type(s)reference • political division • type of sample • species • method of identification • geographic coordinatesSample Characteristic - OrganismLeishmaniaSample Characteristic - LocationNorth America • South America Machine-accessible metadata file describing the reported data:...
Published in Heliyon
Microbiology; Natural product chemistry; Parasitology; Pharmacology; Antimicrobial; Amebiasis; Antiparasitic; Natural products; Plant extracts
Published in Parasites & Vectors
The 5th Post-Kala-Azar Dermal Leishmaniasis (PKDL) Consortium meeting brought together PKDL experts from all endemic areas to review and discuss existing and new data on PKDL. This report summarizes the presentations and discussions and provides the overall conclusions and recommendations.
Background Practical, field-ready age-grading tools for mosquito vectors of disease are urgently needed because of the impact that daily survival has on vectorial capacity. Previous studies have shown that near-infrared spectroscopy (NIRS), in combination with chemometrics and predictive modeling, can forecast the age of laboratory-reared mosquitoe...
Published in Scientific Reports
Viruses are the most abundant biological entities in marine environments, however, despite its potential ecological implications, little is known about virus removal by ambient non-host organisms. Here, we examined the effects of a variety of non-host organisms on the removal of viruses. The marine algal virus PgV-07T (infective to Phaeocystis glob...
