Assessing procedural satisfaction in the pediatric ED: A systematic review.
Published in The American journal of emergency medicine
Regional vitamin C in Bier block reduces the incidence of CRPS-1 following distal radius fracture surgery.
Published in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie
Systemic vitamin C supplementation after wrist fracture has been suggested to reduce the incidence of complex regional pain syndrome (CRPS). This study aimed to evaluate the effect of regional vitamin C in Bier block in the early phase of fracture on CRPS occurrence following surgery for distal radius fractures. Seventy-four patients with isolated ...
Pain-less injection: principles and pearls.
Published in Archives of dermatological research
There has been an exponential growth in the number of dermatologic procedures performed over the past two decades. This surge in procedural volumes is accompanied by increasing utilization of local anesthetics. A proper technique in administering local anesthesia is necessary to minimize pain and promote comfort, as it is often regarded as the most...
Acute renal failure with severe loin pain and patchy renal ischemia after anaerobic exercise.
Published in The American journal of emergency medicine
Acute renal failure with severe loin pain and patchy renal ischemia after anaerobic exercise (ALPE) is gradually gaining recognition. In this case series, we describe the presentation of ALPE in the emergency department setting and its clinical course. In Case 1, an 18-year-old man presented with acute-onset nausea, vomiting, and right flank pain a...
Targeting Nerve Growth Factor for Pain Management in Osteoarthritis-Clinical Efficacy and Safety.
Nerve growth factor (NGF) is a neurotrophin that mediates pain sensitization in pathologic states, including osteoarthritis. In clinical trials, antibodies to NGF reduce pain and improve physical function due to osteoarthritis of the knee or hip and have a long duration of action. Rapidly progressive osteoarthritis is a dose-dependent adverse event...
Prospective patient-reported symptom profiles associated with pediatric acute lymphoblastic leukemia relapse.
Published in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Despite improvements in frontline pediatric acute lymphoblastic leukemia (ALL) treatment, relapse remains a concern. Research in adult cancer patients suggests that patient-reported symptoms may predict survival, but the relationship between symptoms and relapse for pediatric ALL has received little attention. Pediatric patients with ALL (age 2-18 ...
Strategies for increasing gait speed in patients with hip osteoarthritis: their clinical significance and effects on hip...
Published in Arthritis Research & Therapy
BackgroundChanges in gait speed are required in various situations and can be achieved by changing stride length, cadence, or both. Differences in strategies for increasing gait speed may have different effects on hip joint and physical function. The purpose of this study was to determine the effects of strategies for increasing gait speed on hip p...
It is not just menopause: symptom clustering in the Study of Women’s Health Across the Nation
Published in Women's Midlife Health
BackgroundPatterns of symptom clustering in midlife women may suggest common underlying mechanisms or may identify women at risk of adverse health outcomes or, conversely, likely to experience healthy aging. This paper assesses symptom clustering in the Study of Women’s Health Across the Nation (SWAN) longitudinally by stage of reproductive aging a...
Patient and caregiver experiences of living with acute hepatic porphyria in the UK: a mixed-methods study
...Published in Orphanet Journal of Rare Diseases
BackgroundThis study used quantitative and qualitative research methods to analyze how acute hepatic porphyria (AHP) affects patients with varying annualized porphyria attack rates. The overall impact of AHP on patients and caregivers, including their quality of life, was explored. The nature and treatment of acute attacks, experiences of long-term...
Involvement of Macrophages and Spinal Microglia in Osteoarthritis Pain
Published in Current Rheumatology Reports
Purpose of ReviewChronic pain in osteoarthritis (OA) is characterized by pain sensitization, which involves both peripheral and central mechanisms. Studies suggest synovial macrophage and spinal microglia are implicated in pain sensitization in OA. We, therefore, reviewed the evidence of whether synovial macrophage and spinal microglia facilitated ...
