Potent Anti-HIV Activity of Alkyl-Modified DiPPro-Nucleotides
status: published
status: published
Inducing the spontaneous aggregation from casein molecules (i.e. αs1, αs2, β, and κ-casein) into re-assembled casein micelles (RCMs) through the addition of salts as an alternative to native casein micelles, has garnered increasing attention in recent years. In this investigation, re-assembled casein micelles were generated by adding varying amount...
INTRODUCTION: Due to the relatively long life span of rodent models, in order to expediate the identification of novel therapeutics of age related diseases, mouse models of accelerated aging have been developed. In this study we examined skeletal changes in the male and female Klotho mutant (kl/kl) mice and in male and female chronically aged mice ...
L-Ascorbic acid 2-phosphate magnesium (AP-Mg) salt is a Vitamin C derivative frequently used as a raw material in cell culture media for research purposes as well as for Good Manufacturing Practice (GMP)-manufacturing of cell and tissue advanced therapy medicinal products. A selective reversed-phase HPLC (RP-LC) method was developed and validated. ...
Sodium silicate (SS) is investigated as a sustainable green corrosion inhibitor for carbon steel in saline environment under both static and dynamic flow conditions. Potentiodynamic scans and Electrochemical Impedance Spectroscopy revealed that silica is both highly efficient in static and flowing water conditions (up to 98 and 99% resp.). An incre...
Nitrification is a microbial process that converts ammonia (NH3) to nitrite (NO2-) and then to nitrate (NO3-). The first and rate-limiting step in nitrification is ammonia oxidation, which is conducted by both bacteria and archaea. In agriculture, it is important to control this process as high nitrification rates result in NO3- leaching, reduced n...
Optimizing dosages of corrosion inhibitors requires experimental data gathered from time-consuming methods. The current study examines the feasibility of optimizing inhibitor dosages using a model trained for predicting corrosion rates more easily measured using linear polarization resistance in a full-scale cooling water system. A comprehensive st...
Inducing the spontaneous aggregation from casein molecules (i.e. alpha(s1), alpha(s2), beta, and kappa-casein) into re-assembled casein micelles (RCMs) through the addition of salts as an alternative to native casein micelles, has garnered increasing attention in recent years. In this investigation, re-assembled casein micelles were generated by ad...
An innovative and sustainable sodium alginate -sodium silicate (SASS) inhibitor blend is investigated for carbon steel in a dynamic 3 wt% NaCl environment. Potentiodynamic scans and electrochemical impedance spectroscopy are performed to estimate inhibition efficiency (IE) and inhibition mechanism. Synergistic, highly efficient (up to 99%) blends a...
The derivation of nutrient limits in freshwater needs information on the natural background of these nutrients. This study uses floodplain sediment P concentrations to identify human impact over the past 7,500 years and to infer the pristine P concentrations in sediment and water. Floodplain sediment cores from three sites in the lowland Dijle rive...