Published in Molecular neurobiology
Cannabis is an annual herb of the genus Cannabis, with a history of medical use going back thousands of years. However, its abuse causes many side-effects, including confusion of consciousness, alienation, and mental disorders such as schizophrenia and depression. Research conducted on rodents suggests that there are two types of cannabinoid recept...
Published in IOP Conference Series: Earth and Environmental Science
With the growing incorporation of Electric Vehicles (EVs) into the transportation sector, there is an increasing need for reliable and efficient EV charging infrastructure. This paper introduces a near unity Power Factor Correction (PFC) Vienna rectifier is designed specifically for plug-in type three phase EV charging stations. The Vienna rectifie...
Published in Frontiers in Neuroanatomy
A new analysis is presented of the retrograde tracer measurements of connections between anatomical areas of the marmoset cortex. The original normalisation of raw data yields the fractional link weight measure, FLNe. That is re-examined to consider other possible measures that reveal the underlying in link weights. Predictions arising from both ar...
Mood and anxiety disorders are prevalent in today’s society, underscoring the urgent need for more research into effective methods to ease their symptoms and understand their origins. This systematic review focuses on the impact of cognitive reappraisal strategies on the prefrontal cortex (PFC) in individuals with mood and anxiety disorders, expand...
Published in European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology
Serotonin (5-HT) has long been implicated in adaptive emotion regulation as well as the development and treatment of emotional dysregulations in mental disorders. Accumulating evidence suggests a genetic vulnerability may render some individuals at a greater risk for the detrimental effects of transient variations in 5-HT signaling. The present stu...
The WEST (W - for tungsten - Environment in Steady-state Tokamak) platform aims to support the ITER tungsten divertor technology, manufacturing and long pulse operation. For this purpose, the Tore Supra tokamak has been deeply modified (mainly the installation of a lower and upper divertor coil structure), enabling a restart in 2016 and a first pha...
Published in Frontiers in Cellular Neuroscience
In this study, we introduce the importance of elevated membrane potentials (MPs) in the prefrontal cortex (PFC) compared to that in the posterior parietal cortex (PPC), based on new observations of different MP levels in these areas. Through experimental data and spiking neural network modeling, we investigated a possible mechanism of the elevated ...
Published in Annals of the New York Academy of Sciences
A functional interplay of bottom-up and top-down processing allows an individual to appropriately respond to the dynamic environment around them. These processing modalities can be represented as attractor states using a dynamical systems model of the brain. The transition probability to move from one attractor state to another is dependent on the ...
Published in Neuron
Neurons in the prefrontal cortex (PFC) can provide top-down regulation of sensory-affective experiences such as pain. Bottom-up modulation of sensory coding in the PFC, however, remains poorly understood. Here, we examined how oxytocin (OT) signaling from the hypothalamus regulates nociceptive coding in the PFC. In vivo time-lapse endoscopic calciu...
Published in The Journal of neuroscience : the official journal of the Society for Neuroscience
The impact of stress on the formation and expression of memory is well studied, especially on the contributions of stress hormones. But how stress affects brain circuitry dynamically to modulate memory is far less understood. Here, we used male C57BL6/J mice in an auditory fear conditioning as a model system to examine this question and focused on ...
