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with P-tau181 as keyword
Bayoumy, Sherif Verberk, Inge M. W. den Dulk, Ben Hussainali, Zulaiga Zwan, Marissa van der Flier, Wiesje M. Ashton, Nicholas J. Zetterberg, Henrik Blennow, Kaj Vanbrabant, Jeroen
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Published in
Alzheimer's Research & Therapy
IntroductionStudies using different assays and technologies showed highly promising diagnostic value of plasma phosphorylated (P-)tau levels for Alzheimer’s disease (AD). We aimed to compare six P-tau Simoa assays, including three P-tau181 (Eli Lilly, ADx, Quanterix), one P-tau217 (Eli Lilly), and two P-tau231 (ADx, Gothenburg).MethodsWe studied th...
Spiegel, Jonathan Pirraglia, Elizabeth Osorio, Ricardo S Glodzik, Lidia Li, Yi Tsui, Wai Saint Louis, Leslie A Randall, Catherine Butler, Tracy Xu, Jinfeng
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Published in
Journal of Alzheimer's disease : JAD
Cerebrospinal fluid (CSF) measures of phosphorylated-tau (P-tau) 231 and P-tau181 are two biomarkers for the identification of tau pathology as related to Alzheimer's disease (AD). While both are pathologically validated, their relative diagnostic performances are not well known. This cross-sectional diagnostic study of 87 normal (NL) subjects and ...
Buerger, Katharina Frisoni, Giovanni Uspenskaya, Olga Ewers, Michael Zetterberg, Henrik Geroldi, Cristina Binetti, Giuliano Johannsen, Peter Rossini, Paolo Maria Wahlund, Lars-Olof
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Published in
Experimental gerontology
The use of frozen rather than fresh samples renders higher diagnostic accuracy within a multicentre context. We confirmed the feasibility of a multicentre AD biomarker programme for future clinical trials.