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with Ovatodiolide as keyword
Liu, Shao-Cheng Huang, Chih-Ming Chang, Yung-Lung Bamodu, Oluwaseun Adebayo Yeh, Chi-Tai Wang, Hsing-Won Lee, Fei-Peng Lin, Chun-Shu
Published in
European journal of pharmacology
Due to the radiosensitivity of the airway epithelium, radiation-induced sinusitis or bronchitis is not uncommon, and makes mitigation of resulting inflammatory airway diseases a principal goal of many investigations. This study examined whether Ovatodiolide (Ova) sensitizes the human metastatic nasopharyngeal cancer (NPC) cell line, NPC-BM2, to irr...
Liu, Mingche Bamodu, Oluwaseun Adebayo Kuo, Kuang-Tai Lee, Wei-Hwa Lin, Yen-Kuang Wu, Alexander T H M, Hsiao Tzeng, Yew-Min Yeh, Chi-Tai Tsai, Jo-Ting
...
Published in
The American journal of Chinese medicine
The hierarchical tumor propagation or cancer stem cells (CSCs) model of carcinogenesis postulates that like physiologic adult stem cell (ASC), the CSCs positioned at the apex of any tumor population form the crux of tumor evolution with a constitutive regenerative capacity and differentiation potential. The propagation and recurrence of the charact...
Huang, Yan-Jiun Yang, Ching-Kuo Wei, Po-Li Huynh, Thanh-Tuan Whang-Peng, Jacqueline Meng, Tzu-Ching Hsiao, Michael Tzeng, Yew-Ming Wu, Alexander TH Yen, Yun
...
Published in
Journal of Hematology & Oncology
BackgroundAn increased expression of Yes-associated protein (YAP1) has been shown to promote tumorigenesis in many cancer types including colon. However, the role of YAP1 in promoting colon tumorigenesis remains unclear. Here, we demonstrate that YAP1 expression is associated with M2 tumor-associated macrophage polarization and the generation of co...
Bamodu, Oluwaseun Adebayo Huang, Wen-Chien Tzeng, David T W Wu, Alexander Wang, Liang Shun Yeh, Chi-Tai Chao, Tsu-Yi
Published in
Cancer letters
Triple-negative breast cancer (TNBC) is chemotherapy-refractory and associated with poor clinical prognosis. Doxorubicin (Doxo), a class I anthracycline and first-line anticancer agent, effective against a wide spectrum of neoplasms including breast carcinoma, is associated with several cumulative dose-dependent adverse effects, including cardiomyo...
Hou, Yu-Yi Wu, Mu-Ling Hwang, Yu-Chun Chang, Fang-Rong Wu, Yang-Chang Wu, Chin-Chung
Published in
Life sciences
Our results suggest that ovatodiolide causes cell cycle arrest and apoptosis in Ca9-22 cells through disturbance of intracellular redox balance. Furthermore, ovatodiolide may serve as a lead compound for developing new anticancer drugs.
