The Dutch railway system is subject to maintenance, which is carried out by a group of rail contractors who need parking space to park and prepare trains in between projects. The objective of this study is to minimise the total costs as a result of the distance travelled by maintenance trains and the preservation of the included parking locations i...
A process of dry heating alkaline powder containing whey protein (WP) and lactose is used to produce micro-particles that can trap large amounts of water and thus be used in many food applications as a thickening agent. The objective of this study was to optimise the yield of particles formed and the amount of water they trap as well as to minimise...
Published in Water, Air, & Soil Pollution
This study investigated and compared the influence of pretreatments (heat and chemical) on banana peels and their subsequent efficacy in removing toxic metals (Cu, Pb, Zn, Cd) from single and multimetal systems. Banana peels were pretreated using heat (autoclaving, microwaving, boiling) and chemical (acetic acid, nitric acid, NaOH, detergent, metha...
The idea of capturing an asteroid has gained more and more attention in recent years, sparked by rapid technological development and the growing general interest into the subject, both by scientists and commercial parties. The focus of this thesis project lies on transferring a near-Earth asteroid (NEA) from its original orbit to a safe, stable and...
This report presents the main findings of my scientific research after my PhD Thesis and especially in the last 8 years. During this period I have worked on three major topics, which span a wide spectrum of networking aspects: Cloud-RAN architecture for cellular networks, wireless edge-caching, and information diffusion in online social platforms. ...
A dam including a tidal power station with pumping capacity is a new type of flood defence. The negative ecological impact normally associated with closure dams is partially mitigated by including a tidal power station in the structure. Water can move through the tidal power station resulting in a reduced tidal stroke at the created lake. This tida...
Published in BMC Public Health
BackgroundOptimisation processes have the potential to rapidly improve the impact of health interventions. Optimisation can be defined as a deliberate, iterative and data-driven process to improve a health intervention and/or its implementation to meet stakeholder-defined public health impacts within resource constraints. This study aimed to identi...
Published in EURASIP Journal on Wireless Communications and Networking
In this work, one proposes a model to evaluate the optimal deployment of Centralised Radio Access Network (C-RAN) architecture elements, i.e. Base Band processing Units (BBUs) and fronthaul links, in a brown-field scenario, in which traditional base stations are already deployed and a physical network is present. The proposed optimisation framework...
Published in Journal of enzyme inhibition and medicinal chemistry
GPR119 is a promising target for discovery of anti-type 2 diabetes mellitus agents. We described the optimisation of a novel series of pyrimido[5,4-b][1,4]oxazine derivatives as GPR119 agonists. Most designed compounds exhibited good agonistic activities. Among them, compound 10 and 15 demonstrated the potent EC50 values (13 and 12 nM, respectively...
Ou les fluctuations de l'actif disponible à l'épreuve des techniques d'optimisation de la situation patrimoniale du dirigeant
