Krukow, Paweł Domagała, Adam Silverstein, Steven M
Published in
European archives of psychiatry and clinical neuroscience
There is growing evidence of disproportionate retinal thinning in schizophrenia, but doubts are still raised regarding its significance in the context of the neurobiology of the disease. Therefore, we examined whether these abnormalities are significantly associated with neurological soft signs (NSS) which are closely related to the risk of schizop...
Camós-Carreras, Anna Figueras-Roca, Marc Dotti-Boada, Marina Alcubierre, Rafel Casaroli-Marano, Ricardo Pedro Muñoz, Esteban Sánchez-Dalmau, Bernardo
Published in
Cerebellum (London, England)
Spectral domain optical coherence tomography (SD-OCT) allows noninvasive measurements of retinal neuron layers. Here, we evaluate the relationship between clinical features and anatomical SD-OCT measurements in patients with spinocerebellar ataxia type 3 (SCA3) and how they change with time. A retrospective review was conducted on SCA3 patients. Cl...
Ma, Mingrui Powell, Daniel Nassar, Marwa Teckoe, Jason Markl, Daniel Zeitler, J Axel
Pharmaceutical tablets are often coated with a layer of polymeric material to protect the drug from environmental degradation, facilitate the packaging process, and enhance patient compliance. However, the detailed effects of such coating layers on drug release are not well understood. To investigate this, flat-faced pure microcrystalline cellulose...
Kugelman, Jason Alonso-Caneiro, David Read, Scott A. Vincent, Stephen J. Collins, Michael J.
For optimum performance, deep learning methods, such as those applied for retinal and choroidal layer segmentation in optical coherence tomography (OCT) images, require sufficiently large and diverse labelled datasets for training. However, the acquisition and labelling of such data can be difficult or infeasible due to privacy reasons (particularl...
Pighi, Michele Tomai, Fabrizio Fezzi, Simone Pesarini, Gabriele Petrolini, Alessandro Spedicato, Leonardo Tarantini, Giuseppe Ferlini, Marco Calabrò, Paolo Loi, Bruno
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Published in
Clinical research in cardiology : official journal of the German Cardiac Society
Cardiac allograft vasculopathy (CAV) is still the main drawback of heart transplantation (HTx) and percutaneous coronary intervention (PCI) is a palliative measure because of the high incidence of failure. This study aimed to investigate the safety and efficacy of bioresorbable scaffolds (BRSs) as potential novel therapeutic tool for the treatment ...
Jessney, Benn Chen, Xu Gu, Sophie Brown, Adam Obaid, Daniel Costopoulos, Charis Goddard, Martin Shah, Nikunj Garcia-Garcia, Hector Onuma, Yoshinobu
...
BACKGROUND: Optical coherence tomography (OCT) is used widely to guide stent placement, identify higher-risk plaques, and assess mechanisms of drug efficacy. However, a range of common artifacts can prevent accurate plaque classification and measurements, and limit usable frames in research studies. We determined whether pre-processing OCT images c...
Macherey-Meyer, S Meertens, M M Heyne, S Braumann, S Tichelbäcker, T Wienemann, H Mauri, V Baldus, S Adler, C Lee, S
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Published in
Clinical research in cardiology : official journal of the German Cardiac Society
Percutaneous coronary intervention (PCI) is standard of care in patients with acute coronary syndrome (ACS) suitable for interventional revascularization. Intracoronary imaging by optical coherence tomography (OCT) expanded treatment approaches adding diagnostic information and contributing to stent optimization. This meta-analysis aimed to assess ...
Borrelli, Enrico Barresi, Costanza Berni, Alessandro Viggiano, Pasquale Reibaldi, Michele Introini, Ugo Bandello, Francesco
Published in
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
To assess the relationship of optical coherence tomography (OCT) findings and progression to foveal atrophy in a cohort of eyes with extrafoveal geographic atrophy (GA) and age-related macular degeneration (AMD) at inclusion. We retrospectively analyzed 45 participants (45 eyes) with extrafoveal GA at baseline and with 2 years of regular follow-ups...
Hui, Maggie Gunzenhauser, Robert Dillon, Alexander Tsui, Irena
Published in
Case Reports in Ophthalmology
Introduction: We present a case of a patient with preceding vitreomacular traction (VMT) who developed a full-thickness macular hole (FTMH) following his sixth intravitreal aflibercept injection for the treatment of age-related macular degeneration and review the literature on risk factors and pathogenesis of this adverse event. Case Presentation: ...
Pastor, Geoffrey Salleron, Julia Zessler, Astrid Stoebener, Sarah Angioi-Duprez, Karine Berrod, Jean-Paul Conart, Jean-Baptiste
Published in
Ophthalmologica
Introduction: The aim of the study was to determine the prevalence of metamorphopsia following rhegmatogenous retinal detachment (RRD) surgery, as well as associated predictive factors. Methods: A total of 107 eyes successfully operated for RRD underwent metamorphopsia severity assessment using M-CHARTS, and foveal microstructure analysis by spectr...
