Ibrahim Ismail, Ismail K. John, John Ibrahim, Mohamed Al-Hashel, Jasem Yousef
Published in
Case Reports in Neurology
Paraneoplastic neurological syndromes (PNS) associated with anti-CV2/CRMP5 antibodies are rare in the literature. Various clinical manifestations can occur including paraneoplastic limbic encephalitis (PLE). Thymoma is one of the rare causes that can be associated with this syndrome. It has not been reported in the literature in children or adolesc...
Grativvol, Ronnyson Susano Cavalcante, Wagner Cid Palmeira Castro, Luiz Henrique Martins Nitrini, Ricardo Simabukuro, Mateus Mistieri
Published in
Current Oncology Reports
The disorders of the central nervous system associated with cancer by remote immune-mediated mechanisms are a heterogeneous group. These disorders encompass the classic paraneoplastic disorders and the recently recognized autoimmune encephalitis associated with antibodies against neuronal cell surface or synaptic proteins that occur with or without...
Rybacka-Mossakowska, J Ramlau, R Gazdulska, J Gołda-Gocka, I Kozubski, W Michalak, S
Published in
Advances in experimental medicine and biology
Cognitive impairment develops as a clinical manifestation of immune-mediated indirect effects of malignancy in lung cancer patients. This study aimed to evaluate the effects of humoral immune response on cognition in lung cancer patients. Fifty-one lung cancer patients were subjected to neurological examination: Mini Mental State Examination (MMSE)...
Rybacka-Mossakowska, J Ramlau, R Gazdulska, J Gołda-Gocka, I Kozubski, W Michalak, S
Published in
Advances in experimental medicine and biology
Cognitive impairment develops as a clinical manifestation of immune-mediated indirect effects of malignancy in lung cancer patients. This study aimed to evaluate the effects of humoral immune response on cognition in lung cancer patients. Fifty-one lung cancer patients were subjected to neurological examination: Mini Mental State Examination (MMSE)...
Rubio-Agusti, Ignacio Salavert, Miguel Bataller, Luis
Published in
Current Treatment Options in Neurology
Patients with limbic encephalitis and related cortical syndromes develop neurologic and psychiatric symptoms due to autoimmune damage of limbic and extralimbic brain areas. Some patients develop limbic encephalitis as a paraneoplastic manifestation of systemic cancer, where immune tolerance is thought to be lost. Serum and cerebrospinal antibodies ...
Lindeck-Pozza, E. Grisold, W.
Published in
Der Onkologe
HintergrundParaneoplastische neurologische Syndrome (PNS) sind seltene neurologische Erkrankungen, welche mit Tumoren assoziiert auftreten, allerdings weder durch lokale Tumorwirkungen noch indirekt durch vaskuläre, toxische oder metabolische Effekte ausgelöst werden.ZielEine Beschreibung der Klinik, Diagnostik und evidenzbasierten Therapien von PN...
Diard-Detoeuf, Capucine Dangoumau, Audrey Limousin, Nadège Biberon, Julien Vourc'h, Patrick Andres, Christian R. de Toffol, Bertrand Praline, Julien
Published in
Journal of the Neurological Sciences
IntroductionWhether motor neuron diseases (MNDs) can be considered in some cases of paraneoplastic syndromes is controversial. We report a case of rapidly progressive motor neuronopathy following a diagnosis of breast carcinoma, with a presence of anti-Ri antibodies, and a novel SOD1 gene mutation. ObservationAn 80-year-old woman with mucinous aden...