Girgin Ersoy, Zeynep Kayıhan, Ceyhun Tunca, Sedef
Published in
Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
There are different studies that aim to enhance the production of nisin by Lactococcus lactis since its chemical synthesis is not possible. In this study, glutathione (GSH) and pyruvate, which are known to reduce the oxidative stress of cells, have been shown to trigger the production of nisin at both transcriptional and translational levels in L. ...
Cao, Lijie Liang, Dongmei Hao, Panlong Song, Qianqian Xue, Ershu Caiyin, Qinggele Cheng, Zihao Qiao, Jianjun
Published in
Journal of Industrial Microbiology & Biotechnology
Cell wall is closely related to bacterial robustness and adsorption capacity, playing crucial roles in nisin production in Lactococcus lactis. Peptidoglycan (PG), the essential component of cell wall, is usually modified with MurNAc O-acetylation and GlcNAc N-deacetylation, catalyzed by YvhB and XynD, respectively. In this study, increasing the two...
Şimşek, Ömer Buzrul, Sencer Akkoç, Nefise Alpas, Hami Akçelik, Mustafa
Published in
Applied Biochemistry and Biotechnology
The purpose of this study is to determine the survival and nisin production behaviors of two strains of Lactococcus lactis under different stress conditions that represent the food ecosystem. In this respect, the survival ratios of two nisin producers were determined under different pH, temperature, NaCl, and bile salt concentrations. Then, nisin p...
Simsek, Ömer Saris, Per E. J.
Published in
Biotechnology Letters
High specific cellular nisin production was aimed by cycle changing the medium of Lactococcus lactis N8 and LAC48. The highest level of nisin production was reached with the 120 min cycles but maximal production was unstable. In shorter cycles (30 and 60 min) cells could be maintained in a high production state up to the end of the fermentation (28...
Pongtharangku, Thunyarat Demirci, Ali
Published in
Applied Microbiology and Biotechnology
An online removal of nisin by silicic acid coupled with a micro-filter module was proposed as an alternative to reduce detrimental effects caused by adsorption of nisin onto producer, enzymatic degradation by protease, and product inhibition during fermentation. In this study, silicic acid was successfully used to recover nisin from the fermentatio...