Mosbacher, Yossi Khoyratee, Farad Goldin, Miri Kanner, Sivan Malakai, Yenehaetra Silva, Moises Grassia, Filippo Simon, Yoav Ben Cortes, Jesus Barzilai, Ari
...
Published in
Scientific Reports
Restoration of the communication between brain circuitry is a crucial step in the recovery of brain damage induced by traumatic injuries or neurological insults. In this work we present a study of real-time unidirectional communication between a spiking neuronal network (SNN) implemented on digital platform and an in-vitro biological neuronal netwo...
Teepker, M. Peters, M. Vedder, H. Schepelmann, K. Lautenbacher, S.
Published in
Neuropsychobiology
Background: The results of studies examining the response to experimental pain during the menstrual cycle are conflicting because of differences in the definitions of the menstrual period, outcome measures and types of experimental pain stimulation. So far, there have been only a few studies correlating experimental pain with the levels of gonadal ...
Daci, Rrita Natarajan, Sabareesh K. Johnson, Mark D.
The highest viral load for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is found in the lungs, nasopharynx, and oropharynx. Thus, working in close proximity to the face likely represents the greatest risk of SARS-CoV-2 exposure for neurosurgeons, many of whom have contracted and/or died from COVID-19. However, sources of exposure ot...
Ahmad, Imran Azam Rathore, Farooq
Published in
Journal of Clinical Neuroscience
The Coronavirus disease due to SARS-CoV-2 emerged in Wuhan city, China in December 2109 and rapidly spread to more than 200 countries as a global health pandemic. There are more than 2.3 million confirmed cases and around 165,000 fatalities. The primary manifestation is respiratory and cardiac but neurological features are also being reported in th...
Wieckiewicz, Mieszko Bogunia-Kubik, Katarzyna Mazur, Grzegorz Danel, Dariusz Smardz, Joanna Wojakowska, Anna Poreba, Rafal Dratwa, Marta Chaszczewska-Markowska, Monika Winocur, Efraim
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Published in
Scientific Reports
Sleep bruxism (SB) and obstructive sleep apnea (OSA) are co-occurring sleep conditions. The study aimed to evaluate the association of selected single-nucleotide polymorphisms (SNPs) occurring within the genes of the serotonin and dopamine pathways in SB and OSA and investigate the relationship between them. The study group included 100 Caucasian p...
Chen, Bao Ying Ghezzi, Chiara Villegas, Brendon Quon, Andrew Radu, Caius G Witte, Owen N Clark, Peter M
Brain-infiltrating leukocytes contribute to multiple sclerosis (MS) and autoimmune encephalomyelitis and likely play a role in traumatic brain injury, seizure, and stroke. Brain-infiltrating leukocytes are also primary targets for MS disease-modifying therapies. However, no method exists for noninvasively visualizing these cells in a living organis...
Murphy, Lindsay B. Stevenson, John Herbert Straub, Volker
OBJECTIVE: The Global FKRP Registry is a database for individuals with conditions caused by mutations in the Fukutin-Related Protein (FKRP) gene: limb girdle muscular dystrophy R9 (LGMDR9, formerly LGMD2I) and congenital muscular dystrophies MDC1C, Muscle-Eye-Brain Disease and Walker-Warburg Syndrome. The registry seeks to further understand the na...
Bheemanapally, Khaggeswar Ibrahim, Mostafa M. H. Briski, Karen P.
Published in
Scientific Reports
Glutamine (Gln) is converted to excitatory (glutamate, aspartate) and inhibitory (γ-amino butyric acid) amino acid neurotransmitters in brain, and is a source of energy during glucose deprivation. Current research utilized an Analytical Quality by Design approach to optimize levels and combinations of critical gas pressure (sheath, auxiliary, sweep...
Blumenau, Sonja Foddis, Marco Müller, Susanne Holtgrewe, Manuel Bentele, Kajetan Berchtold, Daniel Beule, Dieter Dirnagl, Ulrich Sassi, Celeste
Published in
Scientific Reports
Alzheimer’s disease and small vessel ischemic disease frequently co-exist in the aging brain. However, pathogenic links between these 2 disorders are yet to be identified. Therefore we used Taqman genotyping, exome and RNA sequencing to investigate Alzheimer’s disease known pathogenic variants and pathways: APOE ε4 allele, APP-Aβ metabolism and lat...
Henssen, Dylan Kurt, Erkan van Walsum, Anne-Marie Van Cappellen Kozicz, Tamas van Dongen, Robert Bartels, Ronald
Published in
Scientific Reports
Invasive motor Cortex Stimulation (iMCS) was introduced in the 1990’s for the treatment of chronic neuropathic orofacial pain (CNOP), although its effectiveness remains doubtful. However, CNOP is known to be a heterogeneous group of orofacial pain disorders, which can lead to different responses to iMCS. Therefore, this paper investigated (1) wheth...
