Buck, Jordan M. O’Neill, Heidi C. Stitzel, Jerry A.
Published in
Epigenetics & Chromatin
BackgroundMaternal smoking of traditional or electronic cigarettes during pregnancy, which constitutes developmental nicotine exposure (DNE), heightens the risk of neurodevelopmental disorders including ADHD, autism, and schizophrenia in children. Modeling the intergenerationally transmissible impacts of smoking during pregnancy, we previously demo...
Ibrahim, Rania S. M. Hachem, Rania H.
Published in
Egyptian Journal of Radiology and Nuclear Medicine
BackgroundIn spite of having many classifications for pediatric cerebellar malformations (PCMs), no broadly accepted classification is recommended. Associated neurodevelopmental outcomes in children with PCMs remain poorly defined. Neuroimaging is compulsory for the diagnosis of cerebellar malformation and their associated abnormalities. This artic...
Mangin, Jean-Francois Rivière, Denis Duchesnay, Edouard Cointepas, Yann Gaura, Véronique Verny, Christophe Damier, Philippe Krystkowiak, Pierre Bachoud-Lévi, Anne-Catherine Hantraye, Philippe
...
Published in
NeuroImage. Clinical
Huntington's disease (HD) is an inherited, autosomal dominant disorder that is characteristically thought of as a degenerative disorder. Despite cellular and molecular grounds suggesting HD could also impact normal development, there has been scarce systems-level data obtained from in vivo human studies supporting this hypothesis. Sulcus-specific m...
Ching, Christopher R K Gutman, Boris A Sun, Daqiang Villalon Reina, Julio Ragothaman, Anjanibhargavi Isaev, Dmitry Zavaliangos-Petropulu, Artemis Lin, Amy Jonas, Rachel K Kushan, Leila
...
Published in
The American journal of psychiatry
22q11.2 deletion syndrome (22q11DS) is among the strongest known genetic risk factors for schizophrenia. Previous studies have reported variable alterations in subcortical brain structures in 22q11DS. To better characterize subcortical alterations in 22q11DS, including modulating effects of clinical and genetic heterogeneity, the authors studied a ...
Rolschau, Anne Hald Olesen, Annette Wind Obel, Carsten Olsen, Jørn Wu, Chunsen S. Kofoed, Poul-Erik
Published in
BMC Pediatrics
BackgroundTo estimate the association between post-term delivery and risk of physical disabilities, mental disabilities, and seizures during the first 7 years of life.MethodsData from 57,884 singleton infants born alive in week 39–45 by mothers included in the Danish National Birth Cohort (1997 to 2004) were analyzed, of these 51,268 were born at t...
Severance, Emily G Yolken, Robert H
Published in
Neurobiology of disease
The body's microbiome represents an actively regulated network of novel mechanisms that potentially underlie the etiology and pathophysiology of a wide range of diseases. For complex brain disorders such as schizophrenia, understanding the cellular and molecular pathways that intersect the bidirectional gut-brain axis is anticipated to lead to new ...
D’Mello, Santosh R.
Published in
Developmental Neuroscience
Neurodevelopment is a highly complex process composed of several carefully regulated events starting from the proliferation of neuroepithelial cells and culminating with and refining of neural networks and synaptic transmission. Improper regulation of any of these neurodevelopmental events often results in severe brain dysfunction. Accumulating evi...
Koomar, Tanner Michaelson, Jacob J.
Published in
Current Psychiatry Reports
Purpose of ReviewTo better understand the shared basis of language and mental health, this review examines the behavioral and neurobiological features of aberrant language in five major neuropsychiatric conditions. Special attention is paid to genes implicated in both language and neuropsychiatric disorders, as they reveal biological domains likely...
Stroustrup, Annemarie Bragg, Jennifer B Busgang, Stefanie A Andra, Syam S Curtin, Paul Spear, Emily A Just, Allan C Arora, Manish Gennings, Chris
Published in
Journal of exposure science & environmental epidemiology
In the United States each year, more than 300,000 infants are admitted to neonatal intensive care units (NICU) where they are exposed to a chemical-intensive hospital environment during a developmentally vulnerable period. Although multiple studies have demonstrated elevated phthalate biomarkers in NICU patients, specific sources of NICU-based phth...
Reilhac, Astrid Garlantézec, Ronan Lacroix, Agnès Rouget, Florence Warembourg, Charline Monfort, Christine Le Gléau, Florent Cordier, Sylvaine Viel, Jean-François Chevrier, Cécile
...
Background Exposure to glycol ethers (GEs) is suspected of impairing neurodevelopment in children, but the specific impact on their inhibitory capacity, a central deficit of ADHD, has never been studied. We aimed to assess the impact of prenatal exposure to GEs on the response inhibition of children aged six years. Methods In total, 169 mother-chil...
