Publication search
with NOCICEPTIVE NEURONS as keyword

Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons

Published in Molecular Pain

BackgroundOxaliplatin chemotherapy induced neuropathy is a dose related cumulative toxicity that manifests as tingling, numbness, and chronic pain, compromising the quality of life and leading to discontinued chemotherapy. Patients report marked hypersensitivity to cold stimuli at early stages of treatment, when sensory testing reveals cold and hea...