Pain related to MRgFUS: a merely minor transient adverse event?
...Published in Journal of neurology, neurosurgery, and psychiatry
Resection versus biopsy in patients with glioblastoma (RESBIOP study): study protocol for an international multicentre p...
...
INTRODUCTION: There are no guidelines or prospective studies defining the optimal surgical treatment for glioblastomas in older patients (≥70 years), for those with a limited functioning performance at presentation (Karnofsky Performance Scale ≤70) or for those with tumours in certain locations (midline, multifocal). Therefore, the decision between...
Clinical benefits of therapeutic drug monitoring of vancomycin therapy in patients with postoperative intracerebral hemo...
Published in European journal of hospital pharmacy : science and practice
The objective of this study was to investigate the clinical efficacy and safety of conducting therapeutic drug monitoring (TDM) of vancomycin in patients with postoperative intracerebral haemorrhage. We conducted a retrospective analysis of 435 patients who experienced postoperative cerebral haemorrhage and were treated with vancomycin in the Depar...
Contribution of basal ganglia activity to REM sleep disorder in Parkinson’s disease
...
Published in Journal of Neurology, Neurosurgery, and Psychiatry
Background Rapid eye movement (REM) sleep behaviour disorder (RBD) is one of the most common sleep problems and represents a key prodromal marker in Parkinson’s disease (PD). It remains unclear whether and how basal ganglia nuclei, structures that are directly involved in the pathology of PD, are implicated in the occurrence of RBD. Method Here, in...
Outcomes following surgical interventions for hypothalamic hamartomas: protocol for a systematic review and individual p...
Published in BMJ open
Hypothalamic hamartomas (HHs) are deep-seated congenital lesions that typically lead to pharmacoresistant epilepsy and a catastrophic encephalopathic syndrome characterised by severe neuropsychological impairment and decline in quality of life. A variety of surgical approaches and technologies are available for the treatment of HH-related pharmacor...
Uncovering neuroanatomical correlates of impaired coordinated movement after pallidal deep brain stimulation.
...Published in Journal of neurology, neurosurgery, and psychiatry
The loss of the ability to swim following deep brain stimulation (DBS), although rare, poses a worrisome risk of drowning. It is unclear what anatomic substrate and neural circuitry underlie this phenomenon. We report a case of cervical dystonia with lost ability to swim and dance during active stimulation of globus pallidus internus. We investigat...
Raising standards of accuracy in deep brain stimulation requires consistent definitions and unbiased reporting.
Published in Journal of neurology, neurosurgery, and psychiatry
ABN news.
Published in Practical neurology
Adverse events associated with microsurgial treatment for ruptured intracerebral aneurysms: a prospective nationwide stu...
...Published in Journal of neurology, neurosurgery, and psychiatry
Adverse events (AEs) or complications may arise secondary to the treatment of aneurysmal subarachnoid haemorrhage (SAH). The aim of this study was to identify AEs associated with microsurgical occlusion of ruptured aneurysms, as well as to analyse their risk factors and impact on functional outcome. Patients with aneurysmal SAH admitted to the neur...
Adult-onset epilepsy and risk of traumatic brain injury: a nationwide cohort study.
Published in Journal of neurology, neurosurgery, and psychiatry
A knowledge gap exists regarding the risk of traumatic brain injury (TBI) in patients with epilepsy. Patients with adult-onset epilepsy during 2005-2018 in Finland were studied using retrospective longitudinal national registry-linkage design. Patients with epilepsy (n=35 686; 51% men; mean age 56.6 years) were 1:1 matched to non-epileptic controls...
