Coutinho, Joana O P A Quintanilha, Mônica F Campos, Marina R A Ferreira, Enio de Menezes, Graciéle C A Rosa, Luiz H Rosa, Carlos A Vital, Katia D Fernandes, Simone O A Cardoso, Valbert N
...
Published in
Probiotics and antimicrobial proteins
Mucositis is one of the most strenuous side effects caused by chemotherapy drugs, such as 5-fluorouracil (5-FU), during the treatment of several types of cancers. The disease is so prevalent and aggressive that many patients cannot resist such symptoms. However, despite its frequency and clinical significance, there is no effective treatment to pre...
Liu, Z-P Song, Q-Y Chu, C-L Liu, S-H Ren, Y-X Chen, J Zhang, D-X
Published in
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique
To explore the potential protective effect of Kanglaite injection against radiotherapy-induced mucositis in patients with head and neck cancer. This was an open-label, single-arm, and phase II trial. The primary endpoint was the incidence of grade 3-4 radiation-induced mucositis. The secondary endpoints were hematological toxicity, non-hematologica...
Farina, Roberto Simonelli, Anna Franceschetti, Giovanni Minenna, Luigi Schincaglia, Gian Pietro Riccardi, Orio Trombelli, Leonardo
Published in
Clinical oral investigations
The present study was performed to comparatively evaluate the peri-implant bone stability and conditions of marginal tissues at 3 years following transcrestal and lateral sinus floor elevation (tSFE and lSFE, respectively). Patients included in a parallel-arm randomized trial comparatively evaluating tSFE and lSFE were recalled at 3 years post-surg...
Pires, Hévila de Figueiredo Bezerra, Paula Maria Maracajá da Silva, Victor Borges Ribeiro, Isabella Lima Arrais Serpa, Eliane Batista Medeiros de Sousa, Simone Alves Valença, Ana Maria Gondim
Objective: To determine the occurrence and severity of oral mucositis (OM) and the factors associated with the onset of severe oral mucositis (SOM) in pediatric cancer patients. Material and Methods: This was a longitudinal and prospective study with 85 children and adolescents (aged 0 to 19 years) admitted to the Pediatric Oncology Sector of Napol...
Ueno, Takao Yatsuoka, Wakako Ishiki, Hiroto Miyano, Kanako Uezono, Yasuhito
Published in
BMC Cancer
BackgroundOral mucositis (OM) associated with cancer treatment not only impairs patients’ quality of life but also causes treatment delays or changes. This prospective exploratory study was conducted to evaluate the efficacy of Episil® oral liquid, which is an approved protective formulation for the oral mucosa in patients with OM. The extent of th...
Zhao, Zhibai Wang, Linglin Zhang, Mengna Zhou, Chenyu Wang, Yanting Ma, Jiangmin Fan, Yuan
Published in
Scientific Reports
Oral lichen planus (OLP) is a localized autoimmune disease of the oral mucosa, with an incidence of up to 2%. Although corticosteroids are the first-line treatment, they cause several adverse effects. Quercetin, a naturally occurring compound, has fewer side-effects and provides long-term benefits. Besides, it has powerful anti‑inflammatory activit...
Soni, Tej Prakash Gupta, Anil Kumar Sharma, Lalit Mohan Singhal, Harish Sharma, Shantanu Gothwal, Ravindra Singh
Published in
ORL
Introduction: Oral mucositis is the most common toxicity of chemoradiotherapy treatment of head and neck cancers. The present study was performed to evaluate the effect of a researched turmeric formulation on oral mucositis in patients receiving chemoradiotherapy for oral cancer. Methods: This randomized double-blinded placebo-controlled trial incl...
Parkhideh, Sayeh Zeraatkar, Mohadeseh Moradi, Omid Hajifathali, Abbas Mehdizadeh, Mahshid Tavakoli-Ardakani, Maria
Published in
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
This study aimed to investigate the effects of azithromycin suspension on oral mucositis in patients undergoing hematopoietic stem cell transplantation (HSCT). The study was designed as a single-blind randomized controlled trial in Taleghani medical center affiliated to Shahid Beheshti University of Medical Sciences Tehran Iran. Patients undergoing...
Yoneda, Junya Nishikawa, Sachiko Kurihara, Shigekazu
Published in
BMC Cancer
BackgroundChemotherapy is frequently used in cancer treatment; however, it may cause adverse events, which must be managed. Reactive oxygen species (ROS) have been reported to be involved in the induction of intestinal mucositis and diarrhea, which are common side effects of treatment with fluoropyrimidine 5-fluorouracil (5-FU). Our previous studie...
Ramos-Pinto, Mariana Bitu de Lima Gusmão, Teresa Paula Schmidt-Filho, Jayr Jaguar, Graziella Chagas Martins, Manoela Domingues Alves, Fábio Abreu
Published in
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
To compare the efficacy of intraoral and extraoral photobiomodulation (PBM) protocols for the prevention of oral mucositis (OM) in hematopoietic stem cell transplantation (HSCT) patients. A total of 60 patients was randomized into intraoral PBM (IOPBM) and extraoral PBM (EOPBM) groups. Both PBM protocols were well tolerated and no side effects were...
