Cai, Xiuhong Son, Chang Yun Mao, Junjun Kaur, Divya Zhang, Yingying Khaniya, Umesh Cui, Qiang Gunner, M R
Published in
Biochimica et biophysica acta. Bioenergetics
Cytochrome c Oxidase (CcO) is the terminal electron acceptor in aerobic respiratory chain, reducing O2 to water. The released free energy is stored by pumping protons through the protein, maintaining the transmembrane electrochemical gradient. Protons are held transiently in a proton loading site (PLS) that binds and releases protons driven by the ...
NASTRAN, JURIJ
V okviru diplomske naloge predstavimo postopek analize robusnosti modelov sintetičnih bioloških gradnikov. Postopek analize demonstiramo na primeru modela biološkega procesorja. Robustnost ocenimo na podlagi volumna prostora dopustnih parametrov v visokodimenzionalnem prostoru. Ta volumen izračunamo z uporabo genetskih algoritmov, metode glavnih ko...
Cai, Xiuhong SON, CHANG YUN Mao, Junjun Kaur, Divya Zhang, Yingying Khaniya, Umesh Cui, Qiang Gunner, Marylin R.
Cytochrome c Oxidase (CcO) is the terminal electron acceptor in aerobic respiratory chain, reducing O-2 to water. The released free energy is stored by pumping protons through the protein, maintaining the transmembrane electrochemical gradient. Protons are held transiently in a proton loading site (PLS) that binds and releases protons driven by the...
KO, YOUNG MYOUNG BYON, EUNSHIN PAN, QIYUN LAM, HENRY
Quantile is an important quantity in reliability analysis, as it is related to the resistance level for defining failure events. This study develops a computationally efficient sampling method for estimating extreme quantiles using stochastic black box computer models. Importance sampling has been widely employed as a powerful variance reduction te...
Amirkardoust, Aliasghar Hosseini, Seyed Azim Seyedhosseini, Seyed Mohammad Rabeifard, Hamidreza Akbarpournickghalbrashti, Abbas
Published in
Journal of Applied Engineering Sciences
Reinforced Concrete (RC) structures are a prevalent type of structure. In each year a lot of RC buildings are constructed and there is a large investment on RC buildings. Dual systems (containing RC shear walls and moment resisting frame) and moment resisting frame systems are the most common type of RC buildings in Iran. Earthquake can cause sever...
Kuhlman, Brian
Published in
The Journal of biological chemistry
Proteins perform an amazingly diverse set of functions in all aspects of life. Critical to the function of many proteins are the highly specific three-dimensional structures they adopt. For this reason, there is strong interest in learning how to rationally design proteins that adopt user-defined structures. Over the last 25 years, there has been s...
minghao, gu sun, shiliang liu, yan
In Bayesian machine learning, sampling methods provide the asymptotically unbiased estimation for the inference of the complex probability distributions, where Markov chain Monte Carlo (MCMC) is one of the most popular sampling methods. However, MCMC can lead to high autocorrelation of samples or poor performances in some complex distributions. In ...
Xue, Song Liu, Hao Zheng, Zheng
Published in
International Journal of Molecular Sciences
Many studies have provided evidence suggesting that caspases not only contribute to the neurodegeneration associated with Alzheimer’s disease (AD) but also play essential roles in promoting the underlying pathology of this disease. Studies regarding the caspase inhibition draw researchers’ attention through time due to its therapeutic value in the ...
Rahimi, Hossein Mahsuli, Mojtaba
Published in
Bulletin of Earthquake Engineering
This paper presents a new probabilistic framework for seismic hazard assessment and hazard sensitivity analysis. Hazard in this context means the probability of exceeding a measure of ground shaking intensity, such as peak ground acceleration and spectral acceleration. The main components of the proposed framework include structural reliability met...
Favreau, Jean-Dominique
Artists appreciate vector graphics for their compactness and editability. However many artists express their creativity by sketching, painting or taking photographs. Digitizing these images produces raster graphics. The goal of this thesis is to convert raster graphics into vector graphics that are easy to edit. We cast image vectorization as an en...