Margarita Salas (1938–2019)
Published in Nature
Biochemist whose discoveries led to faster, more-accurate DNA testing. Margarita Salas
Bovine besnoitiosis in an endemically infected dairy cattle herd in Italy: serological and clinical observations, risk f...
Published in Parasitology research
Bovine besnoitiosis (Besnoitia besnoiti) is an emerging parasitic disease of cattle in Europe. This study reports a case of bovine besnoitiosis in a dairy farm housing 217 cattle in Italy. A serological screening was performed on the whole herd using the recommended approach of ELISA and confirmatory Western Blot. Seropositive animals were clinical...
Advances in molecular biology of Paeonia L.
Published in Planta
Molecular biology can serve as a tool to solve the limitations of traditional breeding and cultivation techniques related to flower patterns, the improvement of flower color, and the regulation of flowering and stress resistance. These characteristics of molecular biology ensured its significant role in improving the efficiency of breeding and germ...
The AURORA Study: a longitudinal, multimodal library of brain biology and function after traumatic stress exposure
Adverse posttraumatic neuropsychiatric sequelae (APNS) are common among civilian trauma survivors and military veterans. These APNS, as traditionally classified, include posttraumatic stress, postconcussion syndrome, depression, and regional or widespread pain. Traditional classifications have come to hamper scientific progress because they artific...
Got mutation? ‘Base editors’ fix genomes one nucleotide at a time
Published in Nature
A new class of CRISPR-based tools efficiently corrects point mutations in cell lines, animal models and perhaps the clinic.
Computational design and characterization of nanobody-derived peptides that stabilize the active conformation of the bet...
This study aimed to design and functionally characterize peptide mimetics of the nanobody (Nb) related to the β2-adrenergic receptor (β2-AR) (nanobody-derived peptide, NDP). We postulated that the computationally derived and optimized complementarity-determining region 3 (CDR3) of Nb is sufficient for its interaction with receptor. Sequence-related...
Major Advances and Discoveries in Diabetes - 2019 in Review
Published in Current Diabetes Reports
PurposeThis review is based on a recent invited lecture at the American Diabetes Association’s 79th annual Scientific Sessions entitled “Major Advances and Discoveries in Diabetes - The Year in Review.”Recent FindingsHere I provide a written account of my presentation entitled “Major Discoveries in Diabetes over the Past Year.” I highlight several ...
Analysis of RNA in the estimation of post-mortem interval: a review of current evidence.
Published in International journal of legal medicine
Post-mortem interval (PMI) determination is one of the most important issues in forensic sciences. In the past, forensic scientists provided different approaches (physical, chemical, and entomological) for the estimation of PMI without success.However, advances in molecular biology over the last two decades have allowed us to assess the time-depend...
Highly structured homolog pairing reflects functional organization of the Drosophila genome
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Trans-homolog interactions have been studied extensively in Drosophila, where homologs are paired in somatic cells and transvection is prevalent. Nevertheless, the detailed structure of pairing and its functional impact have not been thoroughly investigated. Accordingly, we generated a diploid cell line from divergent parents and applied haplotype-...
Vitek® MS v3.0 System in the Identification of Filamentous Fungi.
Published in Mycopathologia
Infections caused by filamentous fungi are rising in incidence and became a serious health concern. Their rapid and reliable identification in the clinical laboratory is essential for an early and accurate diagnosis to guide timely therapy. Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) has been reported...
