Les travaux menés dans le cadre de cette thèse, ont été motivés par une problématique issue du domaine hospitalier portant sur l'optimisation de la chaîne logistique alimentaire du centre hospitalier de Troyes (CHT). Le CHT a mis en place des mesures importantes afin de répondre efficacement aux besoins des patients et pour améliorer les conditions...
The Inventory Routing Problem (IRP) is the integration of two supply chain subproblems: inventory management and transportation. A challenge common to all supply chain operations is dealing with uncertainty; this also applies to the IRP. The most common approaches to take into account uncertainties in the literature are “a priori” approaches. “A pr...
The thermo-elastic behaviour of biological macromolecules, such as DNA and proteins, is addressed in a wide field of studies, with plenty of theoretical and practical applications. Mathematical modelling of the macromolecules’ response to deformation and to thermal fluctuations allows the validation of the statistical mechanics of small systems, th...
Cocoa is an important cash crop in Central and West Africa, especially in Cameroon. In this part of the world, cacao production is impacted by several diseases, like the Cocoa Swollen Shoot Virus (CSSV) and the black pod disease, and several pests, like Miridae, Distantiella theobroma and Sahlbergella singularis, causing significant damage to pods ...
Cocoa is an important cash crop in Central and West Africa, especially in Cameroon. In this part of the world, cacao production is impacted by several diseases, like the Cocoa Swollen Shoot Virus (CSSV) and the black pod disease, and several pests, like Miridae, Distantiella theobroma and Sahlbergella singularis, causing significant damage to pods ...
Quelle est la capacité du cœur à se régénérer après un infarctus ? Et comment l'améliorer ? Des modèles mathématiques contribuent à l'étudier.
Pathophysiological mechanisms underlying the seasonal dynamic and epidemic occurrence of bacterial meningitis in the African meningitis belt remain unknown. Regular seasonality (hyperendemicity) is observed for meningococcal and pneumococcal meningitis. Understanding this is critical for better prevention and modelling. The two main hypotheses for ...
This work presents a generic framework to construct trivariate isogeometric meshes of complicated geometry and arbitrary topology required for reduced order model applications. Indeed, structured meshes such as isogeometric or pure hexahedral ones are difficult to obtain in an automatic manner. Statistical shape analysis and reduced order modeling ...
La pile à combustible PEMFC est un générateur électrochimique qui présente notamment un potentiel intéressant pour des applications automobiles et dont l’utilisation pourrait contribuer à répondre aux enjeux environnementaux associés aux transports. La faible durabilité des systèmes pile en général et de la pile en particulier constitue un des verr...
Cette thèse de doctorat introduit le problème de tournées de véhicules avec des demandes dépendantes du temps (CVRP-TDD), le CVRP-TDD robuste et le cumulatif CVRP-TDD dans la logistique humanitaire. Ces problèmes contribuent à la planification de la distribution des kits de secours suite à une catastrophe. Ce problème apparaît lorsque les victimes ...
