Avec le vieillissement de la population, le nombre de personnes atteintes de maladies neurodégénératives telles que la rétinite pigmentaire (RP) et la dégénérescence maculaire liée à l'âge (DMLA) augmentent. La RP se caractérise par une vision périphérique réduite, tandis que la DMLA entraîne une perte de vision au centre du champ visuel, dues à la...
Two-photon polymerization (TPP) enables the 3D fabrication of micro- and nanostructures from biocompatible materials with high resolutions, reaching into the realm of hundreds of nanometers. Such capabilities are crucial for advancing applications in fields like mechanobiology. As microscale technologies evolve, the precise characterization of mate...
The intricate interplay between biochemical and physical cues dictates pluripotent stem cell (PSC) differentiation to form various tissues. While biochemical modulation has been extensively studied, the role of biophysical microenvironments in early lineage commitment remains elusive. Here, we introduce a novel 3D cell culture system combining elec...
Published in IOP Conference Series: Earth and Environmental Science
Challenges of stability and specificity associated with early generation sensors necessitate the fabrication and optimization of microbial biosensors. More so, the global biosensors market size currently valued at USD25.5 billion in 2021 is expected to grow at a compound annual growth rate (CAGR) of 7.5% to USD36.7 billion in 2026. Microbial biosen...
Les cellules solaires commerciales composées d’un empilement d’éléments III-V cru sur substrat de germanium (Ge) sont très largement utilisées dans le domaine industriel spatial. Ces dispositifs photovoltaïques hautes performances peuvent cependant être optimisés. En effet, seule une fraction (environ 5%) de l’épaisseur totale des wafers de Ge util...
A complex network of interconnected neurons forms the brain. This network is disrupted in neurodegenerative diseases---such as Parkinson's disease (PD), and there are limited tools available to study the molecular mechanisms behind the degradation of the neuronal network. This indicates a gap in the understanding of how neurodegenerative diseases a...
This thesis focuses on the study of alternating flows within milli- and sub-millimeter-sized channels. The aim is to contribute to the optimization of a miniature (sub-millimeter dimensions) low-temperature (T
Ion sensitive field effect transistors (ISFETs) are semiconductor sensors that have the capability to determine the selected concentration of a specific ion in a solution. Most modern ISFETs utilize their ion selective properties for glucose monitors for diabetics. However, in this thesis, the ISFET fabricated is for the selective detection of K+. ...
Around 10% of the population will have to go through a catheterization procedure for the treatment of a cardiovascular disease at a certain stage of their lives. During such a procedure, smart catheters will be the "eyes and ears" of the surgeons, significantly improving the diagnosis and treatment. However, there have been very limited improvement...
Silicon (Si) photonics has emerged as one of the most promising technologies for the realization of ultra-dense photonic chips thanks to the mature Si industry, the large wafer size and the optical properties of Si and related materials. One of the major remaining challenges is the integration of high-performance light sources on Si. In particular,...
