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MicroRNA-585 inhibits human glioma cell proliferation by directly targeting MDM2

Published in Cancer Cell International

BackgroundMicroRNAs (miRNAs) are important regulators for cancer cell proliferation. miR-585 has been shown to inhibit the proliferation of several types of cancer, however, little is known about its role in human glioma cells.MethodsmiR-585 levels in human glioma clinical samples and cell lines were examined by quantitative real-time PCR (qRT-PCR)...