Yamada, Risa Shimane, Takuya Kondo, Ayumi Yonezawa, Masako Matsumoto, Toshihiko
Published in
Substance Abuse Treatment, Prevention, and Policy
BackgroundConsuming drugs in conjunction with sexual intercourse may shape the perceived interdependence of drug use and sexual intercourse (PIDS). Additionally, the severity of drug problems may have a significant impact on PIDS. However, this relationship remains unverified. Therefore, this study investigates whether the severity of drug problems...
Oka, Matsuhiko Ito, Koki Koga, Minori Kusumi, Ichiro
Published in
Progress in neuro-psychopharmacology & biological psychiatry
The dopamine and glutamate hypotheses reflect only some of the pathophysiological changes associated with schizophrenia. We have proposed a new "comprehensive progressive pathophysiology model" based on the "dopamine to glutamate hypothesis." Repeated administration of methamphetamine (METH) at a dose of 2.5 mg/kg in rats has been used to assess dy...
Baltes, Amelia Akhtar, Wajiha Birstler, Jen Olson-Streed, Heidi Eagen, Kellene Seal, David Westergaard, Ryan Brown, Randall
Published in
Harm Reduction Journal
IntroductionSkin and soft tissue infections (SSTIs) are among the leading causes of morbidity and mortality for people who inject drugs (PWID). Studies demonstrate that certain injection practices correlate with SSTI incidence among PWID. The opioid epidemic in the USA has particularly affected rural communities, where access to prevention and trea...
Wei, Ze-Xu Wu, Qi Liu, Qing-Shan Cheng, Yong
Published in
Journal of neural transmission (Vienna, Austria : 1996)
Drug dependence may affect the neurotransmitter system levels in the human body. This study recruited 113 healthy control subjects, 118 heroin-dependent patients and 118 methamphetamine-dependent patients and examined the serum 5-HT, dopamine, glutamate and norepinephrine levels in the 349 volunteers. ELISA assays demonstrated that the serum 5-HT l...
Hwang, Jong Su Cha, Eun Hye Park, Byoungduck Ha, Eunyoung Seo, Ji Hae
Published in
Archives of pharmacal research
Methamphetamine (METH) is a powerful psychostimulant that is causing serious health problems worldwide owing to imprudent abuses. Recent studies have suggested that METH has deleterious effects on the blood-brain barrier (BBB). A few studies have also been conducted on the mechanisms whereby METH-induced oxidative stress causes BBB dysfunction. We ...
Shahbazi Sighaldeh, Shirin Zarghami, Fatemeh Shahryari, Ali Mohammadinia, Ali Ebrahimi, Mohsen Jorjani, Teimoor Hamrah, Mohammad Shoaib Charkazi, Abdurrahman
Published in
BMC Public Health
BackgroundCrystal (methamphetamine) is a strong stimulant of addictive substances that affects the central nervous system. The consumption of this substance is increasing among teenagers and adult young people in the country. In this matter, one of the practical and important ways to its control is to identify the factors leading to its first use. ...
Ventura, Fabiana Muga, Mariana Coelho-Santos, Vanessa Fontes-Ribeiro, Carlos A Leitão, Ricardo A Silva, Ana Paula
Published in
Toxicology letters
Methamphetamine (METH) consumption is a health problem that leads to neurological and psychiatric disturbances. The cellular alterations behind these conditions have been extensively investigated and it is now well-established that METH causes cerebrovascular alterations being a key feature in drug-induced neuropathology. Although promising advance...
Osman, Sahar Zhu, Zhu Farag, Mark Groysman, Leonid Dastur, Cyrus Akbari, Yama Stern-Nezer, Sara Stradling, Dana Yu, Wengui
Published in
BMC Neurology
BackgroundMethamphetamine use is an emerging risk factor for intracerebral hemorrhage (ICH). The aim of this study was to investigate the use of urine drug screen (UDS) for identifying methamphetamine-associated ICH.MethodsThis is a retrospective, single-center study of consecutive patients hospitalized with spontaneous ICH from January 2013 to Dec...
Hamel, C. Corace, K. Hersi, M. Rice, D. Willows, M. Macpherson, P. Sproule, B. Flores-Aranda, J. Garber, G. Esmaeilisaraji, L.
...
Published in
Systematic Reviews
BackgroundMethamphetamine use and harms are rising rapidly. Management of patients with methamphetamine use disorder (MUD) and problematic methamphetamine use (PMU) is challenging, with no clearly established best approach; both psychosocial and pharmacologic interventions have been described. Furthermore, given the diversity of individuals that us...
Altshuler, Rachel D Lin, Hongyu Li, Xuan
Published in
Pharmacology, biochemistry, and behavior
Cue-induced drug craving and seeking progressively increases during abstinence. This "incubation of drug craving" phenomenon has been observed in both laboratory animals and humans. Preclinical studies identified several neural mechanisms underlying incubation of drug craving after forced abstinence, primarily focusing on cocaine. Recently, studies...
