Abidi, Wasif Nestoridi, Eirini Feldman, Henry Stefater, Margaret Clish, Clary Thompson, Christopher C Stylopoulos, Nicholas
Published in
Digestive diseases and sciences
While Roux-en-Y gastric bypass (RYGB) is one of the most effective and durable treatment options for obesity and its comorbidities, it is complicated by long-term weight regain in over 20% of patients. We sought to determine the metabolite signatures of serum samples of patients with weight regain (RYGB-WR) after RYGB and features distinguishing th...
Gao, Rumeng Miao, Xiaodong Sun, Chengjing Su, Shulan Zhu, Yue Qian, Dawei Ouyang, Zhen Duan, Jinao
Published in
BMC Complementary Medicine and Therapies
BackgroundFrankincense and myrrh are used as traditional anti-inflammatory and analgesic medicines in China. It has been reported that frankincense and myrrh have significant anti-tumor activities. The present study was designed to investigate the inhibitory efficacy of frankincense ethanol extracts (RXC), myrrh ethanol extracts (MYC), frankincense...
Voerman, Ellis Jaddoe, Vincent W. V. Uhl, Olaf Shokry, Engy Horak, Jeannie Felix, Janine F. Koletzko, Berthold Gaillard, Romy
Published in
Metabolomics
IntroductionAdverse exposures in early life may predispose children to cardio-metabolic disease in later life. Metabolomics may serve as a valuable tool to disentangle the metabolic adaptations and mechanisms that potentially underlie these associations.ObjectivesTo describe the acquisition, processing and structure of the metabolomics data availab...
Elmassry, Moamen M. Mudaliar, Nithya S. Colmer-Hamood, Jane A. San Francisco, Michael J. Griswold, John A. Dissanaike, Sharmila Hamood, Abdul N.
Published in
Metabolomics
IntroductionSepsis is a leading cause of mortality in burn patients. One of the major causes of sepsis in burn patients is Pseudomonas aeruginosa. We hypothesized that during dissemination from infected burn wounds and subsequent sepsis, P. aeruginosa affects the metabolome of the blood resulting in changes to specific metabolites that would serve ...
Shi, Rengfei Zhang, Jin Fang, Biqing Tian, Xiangyang Feng, Yu Cheng, Zepeng Fu, Zhongyu Zhang, Jingjing Wu, Jiaxi
Published in
Nutrition & Metabolism
IntroductionMarathon, as a long-distance aerobic exercise, has become a fashionable or popular sport. However, little is known about the holistic metabolic changes occurring within the serum metabolome of athletes after the completion of a marathon.ObjectivesThe goal of current study was to have an in-depth understanding of the impact of marathon o...
Brocker, Chad N. Velenosi, Thomas Flaten, Hania K. McWilliams, Glenn McDaniel, Kyle Shelton, Shelby K. Saben, Jessica Krausz, Kristopher W. Gonzalez, Frank J. Monte, Andrew A.
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Published in
Human Genomics
IntroductionMetoprolol succinate is a long-acting beta-blocker prescribed for the management of hypertension (HTN) and other cardiovascular diseases. Metabolomics, the study of end-stage metabolites of upstream biologic processes, yield insight into mechanisms of drug effectiveness and safety. Our aim was to determine metabolomic profiles associate...
Dai, Dong Wu, Shu-geng Zhang, Hai-jun Qi, Guang-hai Wang, Jing
Published in
Journal of Animal Science and Biotechnology
BackgroundPrenatal nutrition is crucial for embryonic development and neonatal growth, and has the potential to be a main determinant of life-long health. In the present study, we used a layer chick model to investigate the effects of in ovo feeding (IOF) of L-arginine (Arg) on growth, intestinal development, intestinal microbiota and metabolism. T...
O’Shea, Keiron Misra, Biswapriya B.
Published in
Metabolomics
Metabolomics has evolved as a discipline from a discovery and functional genomics tool, and is now a cornerstone in the era of big data-driven precision medicine. Sample preparation strategies and analytical technologies have seen enormous growth, and keeping pace with data analytics is challenging, to say the least. This review introduces and brie...
Chen, Xiacan Xu, Jiajun Tang, Jing Dai, Xinhua Huang, Haolan Cao, Ruochen Hu, Junmei
Published in
BMC Psychiatry
BackgroundMany studies have related biochemical characteristics to violence and have reported schizophrenia could elevated the risk of violent behaviour. However, the metabolic characteristics of schizophrenia patients with violence (V.SC) are unclear.MethodsTo explore the metabolic characteristics of schizophrenia with violence and to identify pot...
Mironenka, Julia Różalska, Sylwia Soboń, Adrian Bernat, Przemysław
Published in
Ecotoxicology and environmental safety
Strains of Trichoderma harzianum are well-known producers of bioactive secondary metabolites and have a beneficial effect on plants. However, to the best of our knowledge, the effect of the commonly used pesticides on the activity of this fungus is not yet investigated. Therefore, in the present study, the effect of the herbicide 2,4-dichlorophenox...
