Rajoria, Sakshi Nissa, Mehar Un Suvarna, Kruthi Khatri, Harsh Srivastava, Sanjeeva
Published in
Data in brief
Elucidation of molecular markers related to the mounted immune response is crucial for understanding the disease pathogenesis. In this article, we present the mass-spectrometry-based metabolomic and proteomic data of blood plasma of COVID-19 patients collected at two-time points, which showed a transition from non-severe to severe conditions during...
Xu, Fangxu Li, Guode
Published in
Food chemistry
Mechanical damage caused by vibration during transportation can destroy organization structure and reduce the fruit quality. The objective was to reveal the mechanism of hypobaric treatment on energy metabolism in vibration-injured 'Huangguan' pears based on metabolomics. Results showed that hypobaric treatment delayed the decline of adenosine trip...
Shi, Yishuai Wang, Junkui Liu, Chuankai Wang, Yangjun Xu, Qingchao Zhou, Xingyu
Published in
Sensors (Basel, Switzerland)
In this paper, a novel concept for cooperative orbit determination (OD) using inter-spacecraft angle-only measurements is proposed. Different from the conventional cooperative OD that only estimates orbit states, the attitude of the observer spacecraft is considered by incorporating the attitude into the estimated vector. The observability of a two...
Jacobs, Jonathan P Lagishetty, Venu Hauer, Megan C Labus, Jennifer S Dong, Tien S Toma, Ryan Vuyisich, Momchilo Naliboff, Bruce D Lackner, Jeffrey M Gupta, Arpana
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Published in
Microbiome
Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is thought to involve alterations in the gut microbiome, but robust microbial signatures have been challenging to identify. As prior studies have primarily focused on composition, we hypothesized that multi-omics assessment of microbial function incorporating both metatranscr...
Shao, Congxiang Xu, Lishu Lei, Pingguang Wang, Wei Feng, Shiting Ye, Junzhao Zhong, Bihui
Published in
Journal of translational medicine
Nonobese metabolic dysfunction-associated fatty liver disease (MAFLD) is paradoxically associated with improved metabolic and pathological features at diagnosis but similar cardiovascular diseases (CVD) prognosis to obese MAFLD. We aimed to utilize the metabolomics to identify the potential metabolite profiles accounting for this phenomenon. This p...
Strefeler, Abigail Jan, Maxime Quadroni, Manfredo Teav, Tony Rosenberg, Nadia Chatton, Jean-Yves Guex, Nicolas Gallart-Ayala, Hector Ivanisevic, Julijana
Published in
Alzheimer's research & therapy
Alzheimer's disease (AD) is a progressive neurodegenerative disorder that is characterized by altered cellular metabolism in the brain. Several of these alterations have been found to be exacerbated in females, known to be disproportionately affected by AD. We aimed to unravel metabolic alterations in AD at the metabolic pathway level and evaluate ...
Kelly, Rachel S. Giorgio, Rachel T. Chawes, Bo L. Palacios, Natalia I. Gray, Kathryn J. Mirzakhani, Hooman Wu, Ann Blighe, Kevin Weiss, Scott T. Lasky-Su, Jessica
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Published in
Metabolomics
IntroductionPreeclampsia represents a major public health burden worldwide, but predictive and diagnostic biomarkers are lacking. Metabolomics is emerging as a valuable approach to generating novel biomarkers whilst increasing the mechanistic understanding of this complex condition.ObjectivesTo summarize the published literature on the use of metab...
Files, D. Clark Ilaiwy, Amro Parry, Traci L. Gibbs, Kevin W. Liu, Chun Bain, James R. Delbono, Osvaldo Muehlbauer, Michael J. Willis, Monte S.
Published in
Metabolomics
IntroductionOlder patients are more likely to acquire and die from acute respiratory distress syndrome (ARDS) and muscle weakness may be more clinically significant in older persons. Recent data implicate muscle ring finger protein 1 (MuRF1) in lung injury-induced skeletal muscle atrophy in young mice and identify an alternative role for MuRF1 in c...
Eckmann, Jean-Pierre Moses, Elisha Stetter, Olav Tlusty, Tsvi Zbinden, Cyrille
Published in
Frontiers in Computational Neuroscience
We present a theoretical framework using quorum percolation for describing the initiation of activity in a neural culture. The cultures are modeled as random graphs, whose nodes are excitatory neurons with kin inputs and kout outputs, and whose input degrees kin = k obey given distribution functions pk. We examine the firing activity of the populat...
Bakir, Sena Hall, Robert D. de Vos, Ric C.H. Mumm, Roland Kadakal, Çetin Capanoglu, Esra
Drying fruits and vegetables is a long-established preservation method, and for tomatoes, in most cases sun-drying is preferred. Semi-drying is relatively a new application aimed to preserve better the original tomato properties. We have assessed the effects of different drying methods on the phytochemical variation in tomato products using untarge...