Adegboye, Mobolaji Felicia Ojuederie, Omena Bernard Talia, Paola M. Babalola, Olubukola Oluranti
Published in
Biotechnology for Biofuels
The issues of global warming, coupled with fossil fuel depletion, have undoubtedly led to renewed interest in other sources of commercial fuels. The search for renewable fuels has motivated research into the biological degradation of lignocellulosic biomass feedstock to produce biofuels such as bioethanol, biodiesel, and biohydrogen. The model stra...
Pileggi, Marcos Pileggi, Sônia A.V. Sadowsky, Michael J.
Published in
Heliyon
Environmental microbiology; Analytical chemistry; DNA analyses; Metabolic pathways; Cell communication
Torretta, Simone Scagliola, Alessandra Ricci, Luisa Mainini, Francesco Di Marco, Sabrina Cuccovillo, Ivan Kajaste-Rudnitski, Anna Sumpton, David Ryan, Kevin M. Cardaci, Simone
...
Published in
Nature Communications
Mannose is present at trace levels in blood and regulates cancer growth. Here the authors show that supraphysiological levels of mannose can also regulate macrophages, limiting their production of IL-1β and increasing resistance of mice to LPS-induced endotoxemia and DSS-induced colitis.
Getahun, Merid Negash Ahuya, Peter Ngiela, John Orone, Abel Masiga, Daniel Torto, Baldwyn
Published in
Scientific Reports
The sources of animal odours are highly diverse, yet their ecological importance, in host–vector communication, remains unexplored. Here, using the camel (host)–Stomoxys calcitrans (vector) interaction, we collected and analyzed the Volatile Organic Compounds (VOCs) of camels from four of its different odour sources: breath, body (skin), urine, and...
Oliveira, Gabriela L Coelho, Ana R Marques, Ricardo Oliveira, Paulo J
Published in
Biochimica et biophysica acta. Molecular basis of disease
To adapt to tumoral environment conditions or even to escape chemotherapy, cells rapidly reprogram their metabolism to handle adversities and survive. Given the rapid rise of studies uncovering novel insights and therapeutic opportunities based on the role of mitochondria in tumor metabolic programing and therapeutics, this review summarizes most s...
Peltek, Sergey E. Bryanskaya, Alla V. Uvarova, Yuliya E. Rozanov, Aleksey S. Ivanisenko, Timofey V. Ivanisenko, Vladimir A. Lazareva, Elena V. Saik, Olga V. Efimov, Vadim M. Zhmodik, Sergey M.
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Published in
BMC Microbiology
BackgroundThe Uzon Caldera is one of the places on our planet with unique geological, ecological, and microbiological characteristics. Uzon oil is the youngest on Earth. Uzon oil has unique composition, with low proportion of heavy fractions and relatively high content of saturated hydrocarbons. Microbial communities of the «oil site» have a divers...
Neville, Stephanie L. Eijkelkamp, Bart A. Lothian, Amber Paton, James C. Roberts, Blaine R. Rosch, Jason W. McDevitt, Christopher A.
Published in
Communications Biology
Neville et al. investigate how Streptococcus pneumoniae mitigates metal ion stress. Despite cadmium induced dysregulation of central carbon metabolism and lipid membrane homeostasis, they find that S. pneumoniae can remain viable by selectively utilizing predominately metal-independent cellular pathways. This study provides insights into how bacter...
Han, Fei Zhang, Mengru Shang, Hongguo Liu, Zhe Zhou, Weizhi
Published in
Bioresource technology
Elemental sulfur (S0) introduction could achieve the co-existence of heterotrophic denitrification (HDN) and autotrophic denitrification (ADN) in practical organic-limited nitrate wastewater treatment. Until now, changes in key functional species, metabolic pathways and microbial products in the succession process of microbialcommunities based on d...
Xiao, Qingpin Wang, Lei Supekar, Shreyas Shen, Tao Liu, Heng Ye, Fei Huang, Junzhou Fan, Hao Wei, Zhiyi Zhang, Cheng
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Published in
Nature Communications
Human steroid 5α-reductase 2 (SRD5A2) is an integral membrane enzyme and catalyzes 5α-reduction of testosterone to dihydrotestosterone. Structural analysis accompanied by computational and mutagenesis studies reveal the mechanisms of catalysis and inhibition by clinically relevant drugs targeting SRD5A2.
DeCamp, Stephen J. Tsuda, Victor M. K. Ferruzzi, Jacopo Koehler, Stephan A. Giblin, John T. Roblyer, Darren Zaman, Muhammad H. Weiss, Scott T. Kılıç, Ayşe De Marzio, Margherita
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Published in
Scientific Reports
In development of an embryo, healing of a wound, or progression of a carcinoma, a requisite event is collective epithelial cellular migration. For example, cells at the advancing front of a wound edge tend to migrate collectively, elongate substantially, and exert tractions more forcefully compared with cells many ranks behind. With regards to ener...