lammi, mikko j. chengjuan, qu
Cartilage defects and osteoarthritis are health problems which are major burdens on health care systems globally, especially in aging populations. Cartilage is a vulnerable tissue, which generally faces a progressive degenerative process when injured. This makes it the 11th most common cause of global disability. Conservative methods are used to tr...
Lynch, John Pierrehumbert, Raymond
Published in
Frontiers in Sustainable Food Systems
Improved greenhouse gas (GHG) emission efficiency of production has been proposed as one of the biggest potential advantages of cultured meat over conventional livestock production systems. Comparisons with beef are typically highlighted, as it is a highly emissions intensive food product. In this study, we present a more rigorous comparison of the...
de Oliveira, Felipe A. Shahin, Mohamed H. Gong, Yan McDonough, Caitrin W. Beitelshees, Amber L. Gums, John G. Chapman, Arlene B. Boerwinkle, Eric Turner, Stephen T. Frye, Reginald F.
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Published in
Metabolomics
IntroductionWhile atenolol is an effective antihypertensive agent, its use is also associated with adverse events including hyperglycemia and incident diabetes that may offset the benefits of blood pressure lowering. By combining metabolomic and genomic data acquired from hypertensive individuals treated with atenolol, it may be possible to better ...
Du, Xiaoyu Zhou, Yijun Schumperlin, Delia Laganenka, Leanid Lee, Seunghun S. Blugan, Gurdial Hardt, Wolf -Dietrich Persson, Cecilia Ferguson, Stephen J.
Silicon nitride is utilized clinically as a bioceramic for spinal fusion cages, owing to its high strength, osteoconductivity, and antibacterial effects. Nevertheless, silicon nitride exhibits suboptimal damping properties, a critical factor in mitigating traumatic bone injuries and fractures. In fact, there is a scarcity of spinal implants that si...
Atif, Abdul Raouf Aramesh, Morteza Carter, Sarah-Sophia Tenje, Maria Mestres, Gemma
Microfluidics has emerged as a promising approach for assessing cellular behavior in vitro, providing more physiologically relevant cell culture environments with dynamic flow and shear stresses. This study introduces the Universal Biomaterial-on-Chip (UBoC) device, which enables the evaluation of cell response on diverse biomaterial substrates in ...
Wang, Bei Prasad, Sonal Hellman, Oskar Li, Hao Fridberger, Anders Hjort, Klas
High-density interconnect (HDI) technology for liquid metal (LM)-based stretchable printed circuit boards is crucial for expanding their applicability. HDI technology provides high-resolution multilayer circuits with a high density of components, as required for next generation of neuroprobes and ultrasonic and sensor arrays. This study presents a ...
Nilsson, Erica Cannon, Jennifer
The world faces a significant challenge regarding access to prosthetics for amputees. In 2017,it was estimated that there were nearly 58 million amputees worldwide, and this figure isexpected to double by 2050. Despite this, only a small fraction of them have access toprosthetics. The reasons for this inadequate access include high costs, lack of k...
Espling, Klara Ahlström, Agnes Eyrich, Ebba
Additive manufacturing (AM) has evolved since the 1980s. Today it is utilized in the medical technology industry to facilitate the creation of customized implants and surgical guides. Despite its potential to enhance treatment outcomes and reduce healthcare costs, the utilization of AM in Swedish healthcare remains limited due to technical, financi...
Svensson, Josefin Ireblad, Hilma
Amputations occur as a result of accidents, infections, wars, diabetes, natural disasters and deficiencies in healthcare. In 2017, it was estimated that 57.7 million people worldwide were amputees due to these reasons. According to the WHO, World Health Organization, only about one in ten people in need of prosthetics globally have access to them. ...
Gray, Gabrielle Scroggins, Douglas G Wilson, Katlin T Scroggins, Sabrina M
Published in
International journal of molecular sciences
Preeclampsia is the leading cause of maternal-fetal morbidity worldwide. The concept that persistent feto-placental intolerance is important in the pathogenesis of preeclampsia (PreE) has been demonstrated by our lab and others. Arginine vasopressin (AVP) infusion during pregnancy induces cardiovascular, renal, and T helper (TH) cell alterations in...